Shagufta Shafique

Islamabad, IS 42000, Pakistan

Last Updated: 09/26/2026

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Found 12 publications

A Novel Missense Mutation in ERCC8 Co-Segregates with Cerebellar Ataxia in a Consanguineous Pakistani Family.

A Novel Missense Mutation in ERCC8 Co-Segregates with Cerebellar Ataxia in a Consanguineous Pakistani Family.

Journal: Cells

Published: September 08, 2022

E2UbcH5B-derived peptide ligands target HECT E3-E2 binding site and block the Ub-dependent SARS-CoV-2 egression: A computational study.

E2UbcH5B-derived peptide ligands target HECT E3-E2 binding site and block the Ub-dependent SARS-CoV-2 egression: A computational study.

Journal: Computers in biology and medicine

Published: February 02, 2022

Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats.

Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats.

Journal: Journal of inflammation research

Published: October 12, 2020

Structural basis of βTrCP1-associated GLI3 processing.

Structural basis of βTrCP1-associated GLI3 processing.

Journal: Scientific reports

Published: November 14, 2018

Structural basis for renal cancer by the dynamics of pVHL-dependent JADE1 stabilization and β-catenin regulation.

Structural basis for renal cancer by the dynamics of pVHL-dependent JADE1 stabilization and β-catenin regulation.

Journal: Progress in biophysics and molecular biology

Published: August 30, 2018

Structural characterization of β-catenin and RX-5902 binding to phospho-p68 RNA helicase by molecular dynamics simulation.

Structural characterization of β-catenin and RX-5902 binding to phospho-p68 RNA helicase by molecular dynamics simulation.

Journal: Progress in biophysics and molecular biology

Published: February 06, 2018

Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics.

Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics.

Journal: International journal of biological macromolecules

Published: May 03, 2017

Antiviral drug acyclovir exhibits antitumor activity via targeting βTrCP1: Molecular docking and dynamics simulation study.

Antiviral drug acyclovir exhibits antitumor activity via targeting βTrCP1: Molecular docking and dynamics simulation study.

Journal: Journal of molecular graphics & modelling

Published: September 17, 2016

Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis.

Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis.

Journal: Journal of molecular graphics & modelling

Published: August 22, 2016

Elucidation, functional clustering and structural characterization of βTrCP1 substrates through a molecular dynamics study.

Elucidation, functional clustering and structural characterization of βTrCP1 substrates through a molecular dynamics study.

Journal: Molecular bioSystems

Published: May 10, 2016

In silico identification of putative bifunctional Plk1 inhibitors by integrative virtual screening and structural dynamics approach.

In silico identification of putative bifunctional Plk1 inhibitors by integrative virtual screening and structural dynamics approach.

Journal: Journal of theoretical biology

Published: August 06, 2015

Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490.

Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490.

Journal: Journal of biomolecular structure & dynamics

Published: May 29, 2015

Showing 1-12 of 12

Last Updated: 09/26/2026