Shahira M. Nofal

Halwan, C, Egypt

Last Updated: 09/26/2026

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Found 19 publications

Targeting the AMPK/SIRT1-NLRP3 Inflammasome Axis: Simvastatin, Ezetimibe, and Their Combination Attenuate 3-Nitropropionic Acid-Induced Striatal Neurodegeneration in Rats.

Targeting the AMPK/SIRT1-NLRP3 Inflammasome Axis: Simvastatin, Ezetimibe, and Their Combination Attenuate 3-Nitropropionic Acid-Induced Striatal Neurodegeneration in Rats.

Journal: Neuropharmacology
Published: July 09, 2026

Nanocarrier-enhanced simvastatin modulates AMPK-ULK1 pathway and oxidative stress in Alzheimer's disease model.

Nanocarrier-enhanced simvastatin modulates AMPK-ULK1 pathway and oxidative stress in Alzheimer's disease model.

Journal: European journal of pharmacology
Published: August 30, 2025

The enhanced Wnt/β-catenin pathway upregulation by sacubitril/valsartan via neprilysin inhibition compared to valsartan in the rotenone induced Parkinson's disease rat model.

The enhanced Wnt/β-catenin pathway upregulation by sacubitril/valsartan via neprilysin inhibition compared to valsartan in the rotenone induced Parkinson's disease rat model.

Journal: Neuropharmacology
Published: November 26, 2024

The crucial role of beta-catenin in the osteoprotective effect of semaglutide in an ovariectomized rat model of osteoporosis.

The crucial role of beta-catenin in the osteoprotective effect of semaglutide in an ovariectomized rat model of osteoporosis.

Journal: Naunyn-Schmiedeberg's archives of pharmacology
Published: April 26, 2024

Targeting the adenosine monophosphate-activated protein kinase signalling pathway by bempedoic acid attenuates Angiotensin II-induced cardiac remodelling in renovascular hypertension in rats.

Targeting the adenosine monophosphate-activated protein kinase signalling pathway by bempedoic acid attenuates Angiotensin II-induced cardiac remodelling in renovascular hypertension in rats.

Journal: Life sciences
Published: June 11, 2023

Camptothecin Sensitizes Hepatocellular Carcinoma Cells to Sorafenib- Induced Ferroptosis Via Suppression of Nrf2.

Camptothecin Sensitizes Hepatocellular Carcinoma Cells to Sorafenib- Induced Ferroptosis Via Suppression of Nrf2.

Journal: Inflammation
Published: December 12, 2022

Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation.

Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation.

Journal: Life sciences
Published: November 23, 2022

Akt / GSK3β / Nrf2 / HO-1 pathway activation by flurbiprofen protects the hippocampal neurons in a rat model of glutamate excitotoxicity.

Akt / GSK3β / Nrf2 / HO-1 pathway activation by flurbiprofen protects the hippocampal neurons in a rat model of glutamate excitotoxicity.

Journal: Neuropharmacology
Published: February 25, 2021

The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells.

The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells.

Journal: Free radical biology & medicine
Published: March 21, 2020

Lixisenatide Reduced Damage in Hippocampus CA1 Neurons in a Rat Model of Cerebral Ischemia-Reperfusion Possibly Via the ERK/P38 Signaling Pathway.

Lixisenatide Reduced Damage in Hippocampus CA1 Neurons in a Rat Model of Cerebral Ischemia-Reperfusion Possibly Via the ERK/P38 Signaling Pathway.

Journal: Journal of molecular neuroscience : MN
Published: December 21, 2019

ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion.

ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion.

Journal: Life sciences
Published: February 05, 2019

The protective effect of zeranol in cerebral ischemia reperfusion via p-CREB overexpression.

The protective effect of zeranol in cerebral ischemia reperfusion via p-CREB overexpression.

Journal: Life sciences
Published: November 04, 2018
Showing 1-12 of 19

Last Updated: 09/26/2026