Shane C. Wright

Stockholm, AB, Sweden

Last Updated: 09/26/2026

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Found 27 publications

Incretin Signaling Neighborhoods and Adverse Drug Reactions.

Incretin Signaling Neighborhoods and Adverse Drug Reactions.

Journal: Annual review of pharmacology and toxicology

Published: September 10, 2025

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.

Journal: Cell

Published: August 29, 2025

GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathways.

GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathways.

Journal: Cell chemical biology

Published: August 08, 2025

GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathways.

GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathways.

Journal: Cell chemical biology

Published: August 08, 2025

Molecular mechanisms of native ligand selectivity in catecholamine G protein-coupled receptors.

Molecular mechanisms of native ligand selectivity in catecholamine G protein-coupled receptors.

Journal: Nature communications

Published: July 07, 2025

Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: Insights from in vitro analysis.

Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: Insights from in vitro analysis.

Journal: Molecular metabolism

Published: May 02, 2025

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β-arrestin recruitment and the discovery of an allosteric agonist.

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β-arrestin recruitment and the discovery of an allosteric agonist.

Journal: British journal of pharmacology

Published: April 25, 2025

Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention.

Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 05, 2024

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.

GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.

Journal: Cell

Published: June 28, 2024

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling.

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling.

Journal: Science signaling

Published: June 18, 2024

Discovery of a novel inhibitor of macropinocytosis with antiviral activity.

Discovery of a novel inhibitor of macropinocytosis with antiviral activity.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 16, 2024

The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.

The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.

Journal: Molecular metabolism

Published: January 12, 2024

Showing 1-12 of 27

Last Updated: 09/26/2026