Shaofan Hu

No. 174 Shazheng Street
Tanjiagang, 400044, China

Last Updated: 09/26/2026

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Found 29 publications

Curcumin exerts distinct anti-tumor effects mediated by NRF1α from NRF2 via metabolic reprogramming in hepatocellular carcinoma (HepG2).

Curcumin exerts distinct anti-tumor effects mediated by NRF1α from NRF2 via metabolic reprogramming in hepatocellular carcinoma (HepG2).

Journal: Bioorganic chemistry

Published: May 21, 2026

Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.

Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 02, 2026

The metabolism-immune axis in colorectal cancer: remodeling the tumor microenvironment through metabolite signaling.

The metabolism-immune axis in colorectal cancer: remodeling the tumor microenvironment through metabolite signaling.

Journal: Frontiers in immunology

Published: October 30, 2025

Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer.

Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer.

Journal: Signal transduction and targeted therapy

Published: October 23, 2025

Opposing mechanisms by which miRNAs mediate distinct Nrf1 and Nrf2 regulation of epithelial-mesenchymal transition in hepatocellular carcinoma.

Opposing mechanisms by which miRNAs mediate distinct Nrf1 and Nrf2 regulation of epithelial-mesenchymal transition in hepatocellular carcinoma.

Journal: RNA biology

Published: August 21, 2025

The pivotal role of TGF-β/Smad pathway in fibrosis pathogenesis and treatment.

The pivotal role of TGF-β/Smad pathway in fibrosis pathogenesis and treatment.

Journal: Frontiers in oncology

Published: June 18, 2025

Inhibition of NFE2L1 Enables the Tumor-Associated Macrophage Polarization and Enhances Anti-PD1 Immunotherapy in Glioma.

Inhibition of NFE2L1 Enables the Tumor-Associated Macrophage Polarization and Enhances Anti-PD1 Immunotherapy in Glioma.

Journal: CNS neuroscience & therapeutics

Published: February 07, 2025

Deficiency of DDI2 suppresses liver cancer progression by worsening cell survival conditions.

Deficiency of DDI2 suppresses liver cancer progression by worsening cell survival conditions.

Journal: Free radical biology & medicine

Published: December 22, 2024

Deletion of Nrf1α exacerbates oxidative stress-induced cellular senescence by disrupting cell homeostasis.

Deletion of Nrf1α exacerbates oxidative stress-induced cellular senescence by disrupting cell homeostasis.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: December 12, 2024

Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer.

Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer.

Journal: Frontiers in oncology

Published: February 03, 2024

Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.

Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.

Journal: Free radical biology & medicine

Published: November 26, 2023

Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway.

Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway.

Journal: Bioorganic chemistry

Published: November 05, 2023

Showing 1-12 of 29

Last Updated: 09/26/2026