Sharon C. Cunningham

214 Hawkesbury Rd
Westmead, NSW 2145, Australia

Last Updated: 09/26/2026

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Found 23 publications

Functional Editing of the OTC locus by Targeted Integration with Phenotype Correction and Restoration of Physiological Patterns of Expression.

Functional Editing of the OTC locus by Targeted Integration with Phenotype Correction and Restoration of Physiological Patterns of Expression.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: January 28, 2026

Identification of AAV Vector Integration Sites in Primary Human and Macaque Hepatocytes in vivo, and Analysis of Oncogenic Risk.

Identification of AAV Vector Integration Sites in Primary Human and Macaque Hepatocytes in vivo, and Analysis of Oncogenic Risk.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: January 20, 2026

Stable transduction of the neonatal mouse liver using a hybrid rAAV/sleeping beauty transposon gene delivery system.

Stable transduction of the neonatal mouse liver using a hybrid rAAV/sleeping beauty transposon gene delivery system.

Journal: The journal of gene medicine

Published: February 02, 2024

Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency.

Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: December 22, 2023

Recapitulation of Skewed X-Inactivation in Female Ornithine Transcarbamylase-Deficient Primary Human Hepatocytes in the FRG Mouse: A Novel System for Developing Epigenetic Therapies.

Recapitulation of Skewed X-Inactivation in Female Ornithine Transcarbamylase-Deficient Primary Human Hepatocytes in the FRG Mouse: A Novel System for Developing Epigenetic Therapies.

Journal: Human gene therapy

Published: June 23, 2023

Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice.

Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice.

Journal: Molecular therapy. Methods & clinical development

Published: June 28, 2022

Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys.

Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys.

Journal: Molecular therapy. Methods & clinical development

Published: May 26, 2021

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice.

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice.

Journal: Cells

Published: August 03, 2020

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes.

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes.

Journal: JHEP reports : innovation in hepatology

Published: November 27, 2019

Insights into Gene Therapy for Urea Cycle Defects by Mathematical Modeling.

Insights into Gene Therapy for Urea Cycle Defects by Mathematical Modeling.

Journal: Human gene therapy

Published: June 20, 2019

AAV-Mediated Gene Delivery to the Mouse Liver.

AAV-Mediated Gene Delivery to the Mouse Liver.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: February 02, 2019

Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice.

Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice.

Journal: Hepatology communications

Published: January 30, 2019

Showing 1-12 of 23

Last Updated: 09/26/2026