Last Updated: 09/26/2026
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Found 11 publications
Attachment Site Cysteine Thiol pKa Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates.
Journal: Bioconjugate chemistry
Published: September 09, 2017
Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody-Drug Conjugates with Self-Immolative Disulfide Linkers.
Journal: Molecular cancer therapeutics
Published: September 29, 2016
Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.
Journal: Science translational medicine
Published: November 20, 2015
Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: June 15, 2015
Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1.
Journal: Journal of medicinal chemistry
Published: May 20, 2015
An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth.
Journal: Genes & development
Published: May 03, 2014
Mapping in vivo tumor oxygenation within viable tumor by 19F-MRI and multispectral analysis.
Journal: Neoplasia (New York, N.Y.)
Published: August 14, 2013
Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900.
Journal: Molecular cancer therapeutics
Published: July 23, 2013
ImmunoPET imaging of phosphatidylserine in pro-apoptotic therapy treated tumor models.
Journal: Nuclear medicine and biology
Published: June 29, 2012
TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.
Journal: Molecular cell
Published: February 09, 2012
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Last Updated: 09/26/2026