Shekhar Kedia

Cambridge, ENG CB20AH, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Early synaptic pathology is associated with small tau aggregates in Alzheimer's disease.

Early synaptic pathology is associated with small tau aggregates in Alzheimer's disease.

Journal: Acta neuropathologica

Published: August 07, 2025

Rethinking neurodegeneration through a co-proteinopathy lens.

Rethinking neurodegeneration through a co-proteinopathy lens.

Journal: Trends in neurosciences

Published: July 17, 2025

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti-CEACAM5 CAR T-Cell Efficacy Against Colorectal Cancer.

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti-CEACAM5 CAR T-Cell Efficacy Against Colorectal Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: May 28, 2025

SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy.

SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy.

Journal: Cell chemical biology

Published: September 11, 2024

The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide.

The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide.

Journal: eLife

Published: June 12, 2024

Real-time heterogeneity of supramolecular assembly of amyloid precursor protein is modulated by an endocytic risk factor PICALM.

Real-time heterogeneity of supramolecular assembly of amyloid precursor protein is modulated by an endocytic risk factor PICALM.

Journal: Cellular and molecular life sciences : CMLS

Published: April 05, 2023

Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.

Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.

Journal: Frontiers in neuroscience

Published: December 09, 2022

Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains.

Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains.

Journal: Molecular brain

Published: June 09, 2021

Quantifying molecular aggregation by super resolution microscopy within an excitatory synapse from mouse hippocampal neurons.

Quantifying molecular aggregation by super resolution microscopy within an excitatory synapse from mouse hippocampal neurons.

Journal: STAR protocols

Published: May 03, 2021

Alteration in synaptic nanoscale organization dictates amyloidogenic processing in Alzheimer's disease.

Alteration in synaptic nanoscale organization dictates amyloidogenic processing in Alzheimer's disease.

Journal: iScience

Published: August 11, 2020

Nanoscale rearrangement of APP organization as a therapeutic target for Alzheimer's disease.

Nanoscale rearrangement of APP organization as a therapeutic target for Alzheimer's disease.

Journal: Medical hypotheses

Published: June 22, 2020

Real-time nanoscale organization of amyloid precursor protein.

Real-time nanoscale organization of amyloid precursor protein.

Journal: Nanoscale

Published: April 08, 2020

Showing 1-12 of 12

Last Updated: 09/26/2026