Sherif F. Rostom
Jeddah, 21589, Saudi Arabia
Last Updated: 09/26/2026
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Found 28 publications
Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents.
Journal: Scientific reports
Published: January 05, 2026
Biochemical and Molecular Studies on the Role of Celecoxib and Some Related Bipyrazoles in Mitigating Induced Liver Injury in Experimental Animals.
Journal: Drug design, development and therapy
Published: December 13, 2024
A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different Antioxidants.
Journal: Bioorganic chemistry
Published: June 02, 2023
The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl4-Induced Liver Fibrosis in Rats.
Journal: Antioxidants (Basel, Switzerland)
Published: January 27, 2023
Towards the Development of Dual Hypouricemic and Anti-inflammatory Candidates: Design, Synthesis, Stability Studies and Biological Evaluation of Some Mutual Ester Prodrugs of Febuxostat-NSAIDs.
Journal: Bioorganic chemistry
Published: January 03, 2023
Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies.
Journal: Bioorganic chemistry
Published: January 12, 2021
Synthesis of Nucleosides and Non-nucleosides Based 4,6-disubstituted-2-oxo-dihydropyridine-3-carbonitriles as Antiviral Agents.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates))
Published: July 03, 2017
Structure-based development of novel triazoles and related thiazolotriazoles as anticancer agents and Cdc25A/B phosphatase inhibitors. Synthesis, in vitro biological evaluation, molecular docking and in silico ADME-T studies.
Journal: European journal of medicinal chemistry
Published: April 16, 2017
Synthesis, Anti-Inflammatory Activity, and COX-1/2 Inhibition Profile of Some Novel Non-Acidic Polysubstituted Pyrazoles and Pyrano[2,3-c]pyrazoles.
Journal: Archiv der Pharmazie
Published: January 22, 2017
Compounds Containing Azole Scaffolds as Cyclooxygenase Inhibitors: A Review.
Journal: Current topics in medicinal chemistry
Published: June 09, 2015
Synthesis of Some 1,4,6-Trisubstituted-2-oxo-1,2-dihydropyridine-3-carbonitriles and Their Biological Evaluation as Cytotoxic and Antimicrobial Agents.
Journal: Archiv der Pharmazie
Published: May 21, 2015
Microwave-assisted synthesis of certain pyrrolylpyridines, some derived ring systems and their evaluation as anticancer and antioxidant agents.
Journal: European journal of medicinal chemistry
Published: September 18, 2014
Last Updated: 09/26/2026