Shi-liang Huang

Guangdong Provincial Key Laboratory Of Chiral Molecule And Drug Discovery
510006, China

Last Updated: 09/26/2026

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Found 36 publications

Photoredox/Nickel-Catalyzed Decarboxylative Monofluoromethylation of β-Boryl NHPI Esters via Radical 1,2-Boron Migration.

Photoredox/Nickel-Catalyzed Decarboxylative Monofluoromethylation of β-Boryl NHPI Esters via Radical 1,2-Boron Migration.

Journal: Organic letters

Published: July 29, 2026

Discovery of a borylated aza-arene chemotype as a direct HSF1 inhibitor targeting the DNA-binding domain.

Discovery of a borylated aza-arene chemotype as a direct HSF1 inhibitor targeting the DNA-binding domain.

Journal: European journal of medicinal chemistry

Published: March 26, 2026

A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis.

A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis.

Journal: Acta pharmaceutica Sinica. B

Published: September 03, 2025

Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy.

Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: August 02, 2024

L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure.

L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure.

Journal: Diabetes, obesity & metabolism

Published: July 25, 2024

Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.

Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.

Journal: Journal of medicinal chemistry

Published: July 12, 2024

MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II.

MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II.

Journal: Molecules (Basel, Switzerland)

Published: June 30, 2023

Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer.

Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer.

Journal: Journal of medicinal chemistry

Published: May 30, 2023

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex.

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex.

Journal: Journal of medicinal chemistry

Published: September 19, 2022

Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer.

Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer.

Journal: Journal of medicinal chemistry

Published: September 02, 2022

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy.

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy.

Journal: Molecules (Basel, Switzerland)

Published: July 29, 2022

A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation.

A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation.

Journal: British journal of pharmacology

Published: May 21, 2021

Showing 1-12 of 36

Last Updated: 09/26/2026