Shibo Sun
Panjin, 124221, China
Last Updated: 09/26/2026
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Found 31 publications
Isoalantolactone induces AML pyroptosis and potentiates α-PD-1 efficacy by targeting selenoprotein TXNRD1.
Journal: Acta pharmaceutica Sinica. B
Published: August 03, 2025
PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.
Journal: Antioxidants (Basel, Switzerland)
Published: July 22, 2025
Au(III) Schiff base complexes as oxidoreductase inhibitors against carbapenem- and colistin-resistant Gram-negative bacteria via targeting redox active motifs.
Journal: Redox biology
Published: July 01, 2025
Mutational analysis of TXNRD1 reveals the essential role of Trp114 in TRP14 reduction and identifies key determinants of enzymatic activity and thermostability.
Journal: Free radical biology & medicine
Published: May 14, 2025
CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway.
Journal: Cancer drug resistance (Alhambra, Calif.)
Published: February 22, 2025
Principle Investigation and Method Standardization of Inhibition Zone Assay Based on Antimicrobial Peptides Extracted from Black Soldier Fly Larvae.
Journal: Biotech (Basel (Switzerland))
Published: May 11, 2024
Thioredoxin reductase inhibition and glutathione depletion mediated by glaucocalyxin A promote intracellular disulfide stress in gastric cancer cells.
Journal: The FEBS journal
Published: March 26, 2024
Pharmacological Inhibition of TXNRD1 by a Small Molecule Flavonoid Butein Overcomes Cisplatin Resistance in Lung Cancer Cells.
Journal: Biological trace element research
Published: March 09, 2024
Protocol for assaying irreversible inhibitors of thioredoxin reductase 1.
Journal: STAR protocols
Published: February 25, 2024
AML cell-derived exosomes suppress the activation and cytotoxicity of NK cells in AML via PD-1/PD-L1 pathway.
Journal: Cell biology international
Published: February 09, 2024
Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif.
Journal: Redox biology
Published: November 12, 2023
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
Journal: Molecules (Basel, Switzerland)
Published: August 30, 2023
Last Updated: 09/26/2026