Shigeaki Ito

Yokohama, Japan

Last Updated: 09/26/2026

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Found 27 publications

Monocyte migration assay using a vascular-on-a-chip model and its utilization for the evaluation of a heated tobacco product.

Monocyte migration assay using a vascular-on-a-chip model and its utilization for the evaluation of a heated tobacco product.

Journal: Frontiers in toxicology

Published: July 02, 2025

Computational prediction of mutagenicity through comprehensive cell painting analysis.

Computational prediction of mutagenicity through comprehensive cell painting analysis.

Journal: Mutagenesis

Published: March 19, 2025

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation.

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation.

Journal: Frontiers in toxicology

Published: January 22, 2025

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke.

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke.

Journal: Frontiers in toxicology

Published: January 22, 2025

Enhancement of cigarette smoke extract-induced goblet cell metaplasia and hyperplasia exerted through IL-13 receptor α1 expression.

Enhancement of cigarette smoke extract-induced goblet cell metaplasia and hyperplasia exerted through IL-13 receptor α1 expression.

Journal: Toxicology letters

Published: November 14, 2024

High-throughput Bronchus-on-a-Chip system for modeling the human bronchus.

High-throughput Bronchus-on-a-Chip system for modeling the human bronchus.

Journal: Scientific reports

Published: June 17, 2024

RNA sequencing analysis of early-stage atherosclerosis in vascular-on-a-chip and its application for comparing combustible cigarettes with heated tobacco products.

RNA sequencing analysis of early-stage atherosclerosis in vascular-on-a-chip and its application for comparing combustible cigarettes with heated tobacco products.

Journal: Current research in toxicology

Published: December 17, 2023

A revision of the multiple-path particle dosimetry model focusing on tobacco product aerosol dynamics.

A revision of the multiple-path particle dosimetry model focusing on tobacco product aerosol dynamics.

Journal: International journal for numerical methods in biomedical engineering

Published: July 18, 2023

Proof of concept for quantitative adverse outcome pathway modeling of chronic toxicity in repeated exposure.

Proof of concept for quantitative adverse outcome pathway modeling of chronic toxicity in repeated exposure.

Journal: Scientific reports

Published: March 31, 2023

Oxidative stress-mediated epidermal growth factor receptor activation by cigarette smoke or heated tobacco aerosol in human primary bronchial epithelial cells from multiple donors.

Oxidative stress-mediated epidermal growth factor receptor activation by cigarette smoke or heated tobacco aerosol in human primary bronchial epithelial cells from multiple donors.

Journal: Journal of applied toxicology : JAT

Published: December 27, 2022

Human vasculature-on-a-chip with macrophage-mediated endothelial activation: The biological effect of aerosol from heated tobacco products on monocyte adhesion.

Human vasculature-on-a-chip with macrophage-mediated endothelial activation: The biological effect of aerosol from heated tobacco products on monocyte adhesion.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: December 21, 2022

Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette.

Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette.

Journal: Toxicology reports

Published: November 06, 2022

Showing 1-12 of 27

Last Updated: 09/26/2026