Shigeki Yagyu

Matsumoto, Japan

Last Updated: 09/26/2026

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Found 59 publications

A potent and selective PHOX2B promoter-driven oncolytic adenovirus for targeted neuroblastoma therapy.

A potent and selective PHOX2B promoter-driven oncolytic adenovirus for targeted neuroblastoma therapy.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 03, 2026

Transient mRNA-based CD117 CAR T cells effectively target acute myeloid leukemia in vitro for potential use as a preconditioning strategy.

Transient mRNA-based CD117 CAR T cells effectively target acute myeloid leukemia in vitro for potential use as a preconditioning strategy.

Journal: Immuno-oncology technology

Published: March 09, 2026

mRNA-LNP vaccine providing antigen and co-stimulation in the tumor microenvironment enhances CAR T cell function (CART-Vac).

mRNA-LNP vaccine providing antigen and co-stimulation in the tumor microenvironment enhances CAR T cell function (CART-Vac).

Journal: Molecular therapy. Oncology

Published: September 30, 2025

Bispecific Ligand-Based EphB4 CAR-T Cells Generated Using Ephrin-B2 Show Potent Antitumor Activity Against Lung Adenocarcinoma.

Bispecific Ligand-Based EphB4 CAR-T Cells Generated Using Ephrin-B2 Show Potent Antitumor Activity Against Lung Adenocarcinoma.

Journal: Cancer science

Published: June 23, 2025

Trial in progress: phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr).

Trial in progress: phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr).

Journal: Frontiers in oncology

Published: May 22, 2025

Retrospective study of stage IV extracranial germ cell tumors: A report from the Japan Children's Cancer Group.

Retrospective study of stage IV extracranial germ cell tumors: A report from the Japan Children's Cancer Group.

Journal: Pediatrics international : official journal of the Japan Pediatric Society

Published: March 25, 2025

Identifying miRNAs as predictive markers of good prognosis in neuroblastoma.

Identifying miRNAs as predictive markers of good prognosis in neuroblastoma.

Journal: Pediatrics international : official journal of the Japan Pediatric Society

Published: January 13, 2025

Alectinib boosts anti-tumor efficacy of disialoganglioside 2 chimeric antigen receptor T cells in ALK-mutated neuroblastoma by suppressing programmed death-ligand 1.

Alectinib boosts anti-tumor efficacy of disialoganglioside 2 chimeric antigen receptor T cells in ALK-mutated neuroblastoma by suppressing programmed death-ligand 1.

Journal: British journal of cancer

Published: January 01, 2025

Ligand-Based CAR-T Cells Targeting EGFR Exhibit Favorable Antitumor Effects Against Gynecologic Malignancies.

Ligand-Based CAR-T Cells Targeting EGFR Exhibit Favorable Antitumor Effects Against Gynecologic Malignancies.

Journal: Cancer science

Published: October 23, 2024

A Novel Conditionally Replicative Oncolytic Adenovirus under the Control of the SALL4 Promoter Inhibits the Growth of Rhabdoid Tumors.

A Novel Conditionally Replicative Oncolytic Adenovirus under the Control of the SALL4 Promoter Inhibits the Growth of Rhabdoid Tumors.

Journal: Molecular cancer therapeutics

Published: August 19, 2024

Selective JAK2 pathway inhibition enhances anti-leukemic functionality in CD19 CAR-T cells.

Selective JAK2 pathway inhibition enhances anti-leukemic functionality in CD19 CAR-T cells.

Journal: Cancer immunology, immunotherapy : CII

Published: August 04, 2024

Adoptive cell therapy for solid tumors

Adoptive cell therapy for solid tumors

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology

Published: August 04, 2024

Showing 1-12 of 59

Last Updated: 09/26/2026