Shigeru Hishinuma

Kiyose, 2048588, Japan

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 29 publications

Histamine H1 Receptor-Mediated CREB Phosphorylation via Gq Protein Signaling and Arrestin Modulation.

Histamine H1 Receptor-Mediated CREB Phosphorylation via Gq Protein Signaling and Arrestin Modulation.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: January 13, 2026

Endothelin-1 induces Zfp36 family RNA-binding proteins and restrains cytokine and chemokine production in reactive astrocytes.

Endothelin-1 induces Zfp36 family RNA-binding proteins and restrains cytokine and chemokine production in reactive astrocytes.

Journal: The Journal of biological chemistry
Published: October 31, 2025

Roles of astrocytic sonic hedgehog production and its signal for regulation of the blood-brain barrier permeability.

Roles of astrocytic sonic hedgehog production and its signal for regulation of the blood-brain barrier permeability.

Journal: Vitamins and hormones
Published: July 19, 2024

Endothelin-1 increases Na+-K+-2Cl- cotransporter-1 expression in cultured astrocytes and in traumatic brain injury model: An involvement of HIF1α activation.

Endothelin-1 increases Na+-K+-2Cl- cotransporter-1 expression in cultured astrocytes and in traumatic brain injury model: An involvement of HIF1α activation.

Journal: Glia
Published: March 06, 2024

Histamine H1 Receptor-Mediated JNK Phosphorylation Is Regulated by Gq Protein-Dependent but Arrestin-Independent Pathways.

Histamine H1 Receptor-Mediated JNK Phosphorylation Is Regulated by Gq Protein-Dependent but Arrestin-Independent Pathways.

Journal: International journal of molecular sciences
Published: February 26, 2024

Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins.

Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins.

Journal: Biochemical pharmacology
Published: March 15, 2023

Roles of Astrocytic Endothelin ETB Receptor in Traumatic Brain Injury.

Roles of Astrocytic Endothelin ETB Receptor in Traumatic Brain Injury.

Journal: Cells
Published: November 25, 2022

Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice.

Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice.

Journal: Journal of pharmacological sciences
Published: May 09, 2022

Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 Reduces Vasogenic Edema after Traumatic Brain Injury in Mice.

Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 Reduces Vasogenic Edema after Traumatic Brain Injury in Mice.

Journal: Biological & pharmaceutical bulletin
Published: November 01, 2021

Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H1 Receptors.

Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H1 Receptors.

Journal: International journal of molecular sciences
Published: January 30, 2021

Differential Regulation of Bilastine Affinity for Human Histamine H1 Receptors by Lys 179 and Lys 191 via Its Binding Enthalpy and Entropy.

Differential Regulation of Bilastine Affinity for Human Histamine H1 Receptors by Lys 179 and Lys 191 via Its Binding Enthalpy and Entropy.

Journal: International journal of molecular sciences
Published: December 22, 2020

Roles of Lys191 and Lys179 in regulating thermodynamic binding forces of ligands to determine their binding affinity for human histamine H1 receptors.

Roles of Lys191 and Lys179 in regulating thermodynamic binding forces of ligands to determine their binding affinity for human histamine H1 receptors.

Journal: Biochemical pharmacology
Published: May 20, 2020
Showing 1-12 of 29

Last Updated: 09/26/2026