Shigeto Kawai

Chugai Life Science Park Yokohama, 216 Totsuka Cho, Totsuka Ku
Yokohama, 2448602, Japan

Last Updated: 09/26/2026

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Found 12 publications

Molecular analysis of tumor recurrence using established cancer stem cell-line and drug discovery.

Molecular analysis of tumor recurrence using established cancer stem cell-line and drug discovery.

Journal: International journal of clinical oncology
Published: October 22, 2025

Robust and reproducible human intestinal organoid-derived monolayer model for analyzing drug absorption.

Robust and reproducible human intestinal organoid-derived monolayer model for analyzing drug absorption.

Journal: Scientific reports
Published: January 21, 2025

Colorectal cancer cell line-derived organoid model with stem cell properties captures the regrowing state of residual cancer cells after neoadjuvant chemotherapy.

Colorectal cancer cell line-derived organoid model with stem cell properties captures the regrowing state of residual cancer cells after neoadjuvant chemotherapy.

Journal: Cell death discovery
Published: November 01, 2024

Development of rat duodenal monolayer model with effective barrier function from rat organoids for ADME assay.

Development of rat duodenal monolayer model with effective barrier function from rat organoids for ADME assay.

Journal: Scientific reports
Published: April 03, 2023

Generation of a lung squamous cell carcinoma three-dimensional culture model with keratinizing structures.

Generation of a lung squamous cell carcinoma three-dimensional culture model with keratinizing structures.

Journal: Scientific reports
Published: September 14, 2021

Continuous formation of small clusters with LGR5-positive cells contributes to tumor growth in a colorectal cancer xenograft model.

Continuous formation of small clusters with LGR5-positive cells contributes to tumor growth in a colorectal cancer xenograft model.

Journal: Laboratory investigation; a journal of technical methods and pathology
Published: January 28, 2020

Tissue-specific effects of an anti-desmoglein-3 ADCC antibody due to expression of the target antigen and physiological characteristics of the mouse vagina.

Tissue-specific effects of an anti-desmoglein-3 ADCC antibody due to expression of the target antigen and physiological characteristics of the mouse vagina.

Journal: Journal of toxicologic pathology
Published: April 18, 2019

Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments.

Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments.

Journal: Scientific reports
Published: March 11, 2019

Generation of an anti-desmoglein 3 antibody without pathogenic activity of pemphigus vulgaris for therapeutic application to squamous cell carcinoma.

Generation of an anti-desmoglein 3 antibody without pathogenic activity of pemphigus vulgaris for therapeutic application to squamous cell carcinoma.

Journal: Journal of biochemistry
Published: January 18, 2018

A simple method for histopathological evaluation of organoids.

A simple method for histopathological evaluation of organoids.

Journal: Journal of toxicologic pathology
Published: October 13, 2017

Generation and characterization of monoclonal antibodies against human LGR6.

Generation and characterization of monoclonal antibodies against human LGR6.

Journal: Journal of biochemistry
Published: May 18, 2016

Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors.

Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors.

Journal: PloS one
Published: August 22, 2013
Showing 1-12 of 12

Last Updated: 09/26/2026