Shimin H. Le

Singapore, Singapore

Last Updated: 09/26/2026

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Found 49 publications

Force-dependent structural dynamics of the giant nesprin-2.

Force-dependent structural dynamics of the giant nesprin-2.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 23, 2026

Single-molecule magnetic tweezers reveal distinct dynamics and enhanced mechanical stability of ssDNA 31 and 52 knots.

Single-molecule magnetic tweezers reveal distinct dynamics and enhanced mechanical stability of ssDNA 31 and 52 knots.

Journal: Nucleic acids research
Published: July 29, 2025

Salt-bridge mediated cooperativity and mechanical stabilization of tandem spectrin repeats.

Salt-bridge mediated cooperativity and mechanical stabilization of tandem spectrin repeats.

Journal: Nanoscale horizons
Published: June 10, 2025

Anomalous Force-Dependent Transition Rates Unveil Dual Pathways in Folding and Unfolding Dynamics of Acyl-coenzyme A Binding Protein.

Anomalous Force-Dependent Transition Rates Unveil Dual Pathways in Folding and Unfolding Dynamics of Acyl-coenzyme A Binding Protein.

Journal: The journal of physical chemistry letters
Published: February 28, 2025

Folding and Misfolding Dynamics of Irisin Protein Revealed by Single-Molecule Magnetic Tweezers.

Folding and Misfolding Dynamics of Irisin Protein Revealed by Single-Molecule Magnetic Tweezers.

Journal: The journal of physical chemistry letters
Published: November 22, 2024

Mechanically weak and highly dynamic state of mechanosensitive titin Ig domains induced by proline isomerization.

Mechanically weak and highly dynamic state of mechanosensitive titin Ig domains induced by proline isomerization.

Journal: Nature communications
Published: September 11, 2024

Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction.

Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 05, 2024

Effect of ssDNA ligand in modulating the folding and unfolding dynamics of cold shock protein BcCsp.

Effect of ssDNA ligand in modulating the folding and unfolding dynamics of cold shock protein BcCsp.

Journal: Physical review. E
Published: July 16, 2024

Ligand-dependent folding and unfolding dynamics and free energy landscapes of acylphosphatase.

Ligand-dependent folding and unfolding dynamics and free energy landscapes of acylphosphatase.

Journal: Soft matter
Published: April 19, 2024

Exploring the free energy landscape of proteins using magnetic tweezers.

Exploring the free energy landscape of proteins using magnetic tweezers.

Journal: Methods in enzymology
Published: March 16, 2024

Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification.

Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification.

Journal: Nature communications
Published: January 27, 2024

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood.

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood.

Journal: ACS sensors
Published: August 15, 2023
Showing 1-12 of 49

Last Updated: 09/26/2026