Shin-ichi Tsunoda

Kobe, Japan

Last Updated: 09/26/2026

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Found 53 publications

TNFR2 signaling promotes monocytic-MDSC differentiation and production of immunosuppressive mediators.

TNFR2 signaling promotes monocytic-MDSC differentiation and production of immunosuppressive mediators.

Journal: FEBS letters

Published: September 01, 2025

Ovalbumin-induced food allergy suppression via regulatory T cell expansion mediated by a TNFR2 agonist in mice.

Ovalbumin-induced food allergy suppression via regulatory T cell expansion mediated by a TNFR2 agonist in mice.

Journal: Biochemical and biophysical research communications

Published: October 18, 2024

Thermostability and binding properties of single-chained Fv fragments derived from therapeutic antibodies.

Thermostability and binding properties of single-chained Fv fragments derived from therapeutic antibodies.

Journal: Protein science : a publication of the Protein Society

Published: February 10, 2024

An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering.

An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering.

Journal: Biochemical and biophysical research communications

Published: December 21, 2023

Functional Study of TNFR2 Signaling and Drug Discovery Using a Protein Engineering Approach

Functional Study of TNFR2 Signaling and Drug Discovery Using a Protein Engineering Approach

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Published: November 30, 2022

Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells.

Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells.

Journal: Scientific reports

Published: November 04, 2022

Characterization of a TNFR2-Selective Agonistic TNF-α Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.

Characterization of a TNFR2-Selective Agonistic TNF-α Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: July 24, 2020

Structural optimization of a TNFR1-selective antagonistic TNFα mutant to create new-modality TNF-regulating biologics.

Structural optimization of a TNFR1-selective antagonistic TNFα mutant to create new-modality TNF-regulating biologics.

Journal: The Journal of biological chemistry

Published: January 20, 2020

A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer.

A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer.

Journal: Scientific reports

Published: October 02, 2018

Development of a Fundamental Technology to Seek Drug Targets, and Its Application to Cancer Targeting Therapy

Development of a Fundamental Technology to Seek Drug Targets, and Its Application to Cancer Targeting Therapy

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Published: July 03, 2018

Neutrophil Depletion Exacerbates Pregnancy Complications, Including Placental Damage, Induced by Silica Nanoparticles in Mice.

Neutrophil Depletion Exacerbates Pregnancy Complications, Including Placental Damage, Induced by Silica Nanoparticles in Mice.

Journal: Frontiers in immunology

Published: April 25, 2018

Modifying the Surface of Silica Nanoparticles with Amino or Carboxyl Groups Decreases Their Cytotoxicity to Parenchymal Hepatocytes.

Modifying the Surface of Silica Nanoparticles with Amino or Carboxyl Groups Decreases Their Cytotoxicity to Parenchymal Hepatocytes.

Journal: Biological & pharmaceutical bulletin

Published: May 02, 2017

Showing 1-12 of 53

Last Updated: 09/26/2026