Shinichiro Horiuchi

Kawasaki, 2109501, Japan

Last Updated: 09/26/2026

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Found 9 publications

An oxygen-permeable, stirrer-pump-integrated liver-heart microphysiological system enables time-resolved analysis in PK-PD relationships of metabolism-dependent cardiotoxicity.

An oxygen-permeable, stirrer-pump-integrated liver-heart microphysiological system enables time-resolved analysis in PK-PD relationships of metabolism-dependent cardiotoxicity.

Journal: NAM journal

Published: May 22, 2026

Stable and functional human intestinal epithelium derived from induced pluripotent stem cells.

Stable and functional human intestinal epithelium derived from induced pluripotent stem cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: April 26, 2025

Considerations for developing CYP induction assays in hepatocytes: Insights from a multilaboratory study.

Considerations for developing CYP induction assays in hepatocytes: Insights from a multilaboratory study.

Journal: European journal of cell biology

Published: September 30, 2024

Examination of common culture medium for human hepatocytes and engineered heart tissue: Towards an evaluation of cardiotoxicity associated with hepatic drug metabolism in vitro.

Examination of common culture medium for human hepatocytes and engineered heart tissue: Towards an evaluation of cardiotoxicity associated with hepatic drug metabolism in vitro.

Journal: PloS one

Published: May 15, 2024

Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.

Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.

Journal: Archives of toxicology

Published: November 08, 2023

Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells.

Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells.

Journal: Stem cell research & therapy

Published: September 03, 2023

Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds.

Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds.

Journal: The Journal of toxicological sciences

Published: April 30, 2023

Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics.

Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics.

Journal: Pharmaceutics

Published: November 25, 2022

Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation.

Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation.

Journal: Scientific reports

Published: May 26, 2022

Showing 1-9 of 9

Last Updated: 09/26/2026