Shirui Wang

Chengdu, 611137, China

Last Updated: 09/26/2026

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Found 16 publications

Nanoparticle-Induced Breast Cancer Cell Death: The Associated Mechanisms of Seven Major Cell Death Pathways in Preclinical Models and a Cross-Validation Model.

Nanoparticle-Induced Breast Cancer Cell Death: The Associated Mechanisms of Seven Major Cell Death Pathways in Preclinical Models and a Cross-Validation Model.

Journal: Cells

Published: February 11, 2026

Organ-level translocation and tissue-specific accumulation of micro- and nanoplastics in wild birds.

Organ-level translocation and tissue-specific accumulation of micro- and nanoplastics in wild birds.

Journal: Journal of hazardous materials

Published: September 03, 2025

Design, synthesis and biological evaluation of anti-HIV-1 Vif inhibitors based on prodrug strategy.

Design, synthesis and biological evaluation of anti-HIV-1 Vif inhibitors based on prodrug strategy.

Journal: Bioorganic & medicinal chemistry letters

Published: April 17, 2025

Assessing microplastic and nanoplastic contamination in bird lungs: evidence of ecological risks and bioindicator potential.

Assessing microplastic and nanoplastic contamination in bird lungs: evidence of ecological risks and bioindicator potential.

Journal: Journal of hazardous materials

Published: November 06, 2024

Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy.

Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy.

Journal: Journal of medicinal chemistry

Published: June 18, 2024

Synthesis and identification of a selective FGFR2 degrader with potent antiproliferative effects in gastric cancer.

Synthesis and identification of a selective FGFR2 degrader with potent antiproliferative effects in gastric cancer.

Journal: European journal of medicinal chemistry

Published: June 07, 2024

Novel Amphiphilic PROTAC with Enhanced Pharmacokinetic Properties for ALK Protein Degradation.

Novel Amphiphilic PROTAC with Enhanced Pharmacokinetic Properties for ALK Protein Degradation.

Journal: Journal of medicinal chemistry

Published: June 05, 2024

Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1.

Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1.

Journal: Bioorganic & medicinal chemistry letters

Published: February 28, 2024

Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.

Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.

Journal: European journal of medicinal chemistry

Published: August 10, 2023

Development of PROTAC degrader probe of CDK4/6 based on DCAF16.

Development of PROTAC degrader probe of CDK4/6 based on DCAF16.

Journal: Bioorganic chemistry

Published: March 21, 2023

Discovery of the GSH responsive "Y-PROTACs" targeting ALK and CDK4/6 as a potential treatment for cancer.

Discovery of the GSH responsive "Y-PROTACs" targeting ALK and CDK4/6 as a potential treatment for cancer.

Journal: European journal of medicinal chemistry

Published: October 21, 2022

Synthesis and biological evaluation of a novel c-Myc inhibitor against colorectal cancer via blocking c-Myc/Max heterodimerization and disturbing its DNA binding.

Synthesis and biological evaluation of a novel c-Myc inhibitor against colorectal cancer via blocking c-Myc/Max heterodimerization and disturbing its DNA binding.

Journal: European journal of medicinal chemistry

Published: August 04, 2022

Showing 1-12 of 16

Last Updated: 09/26/2026