Shisheng Wang

State Key Laboratory Of Fine Chemicals
Dalian, 116024, China

Last Updated: 09/26/2026

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Found 27 publications

The novel oleanolic acid derivative ZQL-4c modulates trastuzumab resistance in HER2+ breast cancer by inhibiting SCD-mediated lipid metabolism disorders.

The novel oleanolic acid derivative ZQL-4c modulates trastuzumab resistance in HER2+ breast cancer by inhibiting SCD-mediated lipid metabolism disorders.

Journal: Cancer cell international

Published: April 02, 2026

Design and synthesis of Sorafenib analogues and evaluation of their ferroptosis-inducing effects in tumor cells.

Design and synthesis of Sorafenib analogues and evaluation of their ferroptosis-inducing effects in tumor cells.

Journal: Bioorganic & medicinal chemistry

Published: February 15, 2025

A novel integrated diagnostic and therapeutic ferroptosis inhibitor based on a phenothiazine scaffold with ROS-Responsive strategy.

A novel integrated diagnostic and therapeutic ferroptosis inhibitor based on a phenothiazine scaffold with ROS-Responsive strategy.

Journal: Bioorganic & medicinal chemistry

Published: February 07, 2025

Corrigendum "Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells" [Phytomedicine 2021:91:153711].

Corrigendum "Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells" [Phytomedicine 2021:91:153711].

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: December 13, 2024

ZQL-4c exerts anti-tumor effects by specifically targeting SCD1 in triple-negative breast cancer both in vitro and in vivo.

ZQL-4c exerts anti-tumor effects by specifically targeting SCD1 in triple-negative breast cancer both in vitro and in vivo.

Journal: Chinese medical journal

Published: December 01, 2024

Synthesis and antitumor effects of novel betulinic acid derivatives bearing electrophilic moieties.

Synthesis and antitumor effects of novel betulinic acid derivatives bearing electrophilic moieties.

Journal: Bioorganic & medicinal chemistry

Published: October 10, 2024

Discovery of Daclatasvir as a potential PD-L1 inhibitor from drug repurposing.

Discovery of Daclatasvir as a potential PD-L1 inhibitor from drug repurposing.

Journal: Bioorganic chemistry

Published: June 02, 2024

N-((1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-methylene-3-oxo-olean-12-en-28-amide Induces Apoptosis in Human Breast Cancer Cells by Stimulating Oxidative Stress and Inhibiting the Notch-Akt Signaling Pathway.

N-((1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-methylene-3-oxo-olean-12-en-28-amide Induces Apoptosis in Human Breast Cancer Cells by Stimulating Oxidative Stress and Inhibiting the Notch-Akt Signaling Pathway.

Journal: Oxidative medicine and cellular longevity

Published: March 03, 2022

An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.

An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.

Journal: Cell biology international

Published: December 02, 2021

An ultrasound-driven immune-boosting molecular machine for systemic tumor suppression.

An ultrasound-driven immune-boosting molecular machine for systemic tumor suppression.

Journal: Science advances

Published: October 20, 2021

Total synthesis and biological evaluation of 7-hydroxyneolamellarin A as hypoxia-inducible factor-1α inhibitor for cancer therapy.

Total synthesis and biological evaluation of 7-hydroxyneolamellarin A as hypoxia-inducible factor-1α inhibitor for cancer therapy.

Journal: Bioorganic & medicinal chemistry letters

Published: June 08, 2021

Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of cancer cells.

Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of cancer cells.

Journal: Bioorganic chemistry

Published: June 03, 2021

Showing 1-12 of 27

Last Updated: 09/26/2026