Shoukat Dedhar

Vancouver, BC, Canada

Last Updated: 09/26/2026

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Found 132 publications

Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis-induced tumor cell death.

Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis-induced tumor cell death.

Journal: European journal of medicinal chemistry

Published: July 13, 2025

Identification of intratumoral bacteria that enhance breast tumor metastasis.

Identification of intratumoral bacteria that enhance breast tumor metastasis.

Journal: mBio

Published: February 11, 2025

Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma.

Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma.

Journal: Oncogene

Published: December 05, 2024

Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis.

Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis.

Journal: Communications biology

Published: December 03, 2024

"Several birds with one stone": exploring the potential of AI methods for multi-target drug design.

"Several birds with one stone": exploring the potential of AI methods for multi-target drug design.

Journal: Molecular diversity

Published: August 16, 2024

Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.

Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.

Journal: Cancer & metabolism

Published: June 02, 2024

PrPC controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up.

PrPC controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up.

Journal: Oncogene

Published: May 23, 2024

Combination treatment with histone deacetylase and carbonic anhydrase 9 inhibitors shows therapeutic potential in experimental diffuse intrinsic pontine glioma.

Combination treatment with histone deacetylase and carbonic anhydrase 9 inhibitors shows therapeutic potential in experimental diffuse intrinsic pontine glioma.

Journal: Brain tumor pathology

Published: March 06, 2024

Co-vulnerabilities of inhibiting carbonic anhydrase IX in ferroptosis-mediated tumor cell death.

Co-vulnerabilities of inhibiting carbonic anhydrase IX in ferroptosis-mediated tumor cell death.

Journal: Frontiers in molecular biosciences

Published: October 24, 2023

Persister cell plasticity in tumour drug resistance.

Persister cell plasticity in tumour drug resistance.

Journal: Seminars in cell & developmental biology

Published: August 04, 2023

A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells.

A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells.

Journal: Molecular cancer therapeutics

Published: January 19, 2023

Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside.

Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside.

Journal: Cancers

Published: June 23, 2022

Showing 1-12 of 132

Last Updated: 09/26/2026