Shu Chen

Zhenjiang, China

Last Updated: 09/26/2026

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Found 8 publications

JOSD1 drives hepatocellular carcinoma malignancy by modulating the ubiquitination-lactylation switch on PGAM1.

JOSD1 drives hepatocellular carcinoma malignancy by modulating the ubiquitination-lactylation switch on PGAM1.

Journal: Gut

Published: October 20, 2025

Landscape screening identifies the lactate-modifying enzyme AARS2 as a master regulator and therapeutic target in hepatocellular carcinoma.

Landscape screening identifies the lactate-modifying enzyme AARS2 as a master regulator and therapeutic target in hepatocellular carcinoma.

Journal: Gut

Published: October 20, 2025

Lactate metabolism and lactylation in cancer: from pathogenesis to therapeutic advances.

Lactate metabolism and lactylation in cancer: from pathogenesis to therapeutic advances.

Journal: Signal transduction and targeted therapy

Published: December 19, 2024

Hypomethylation-Enhanced F-Box Protein 32 Promotes Hepatocellular Carcinogenesis via Ubiquitin-Mediated PHLPP2 Degradation.

Hypomethylation-Enhanced F-Box Protein 32 Promotes Hepatocellular Carcinogenesis via Ubiquitin-Mediated PHLPP2 Degradation.

Journal: MedComm

Published: November 13, 2024

Profile and clinical significance of SPARCL1 and its prognostic significance in breast cancer.

Profile and clinical significance of SPARCL1 and its prognostic significance in breast cancer.

Journal: Oncology letters

Published: May 01, 2024

Retraction Note: GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway.

Retraction Note: GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway.

Journal: Cancer cell international

Published: February 09, 2024

COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.

COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.

Journal: BioMed research international

Published: January 29, 2023

GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway.

GPX8 is transcriptionally regulated by FOXC1 and promotes the growth of gastric cancer cells through activating the Wnt signaling pathway.

Journal: Cancer cell international

Published: August 04, 2020

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Last Updated: 09/26/2026