Shuang Hu

NMPA Key Laboratory For Research And Evaluation Of Drug Metabolism & Guangdong Provincial Key Laboratory Of New Drug Screening & Guangdong Hong Kong Macao Joint Laboratory For New Drug Screening
Guangzhou, China

Last Updated: 09/26/2026

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Found 13 publications

Gut microbiota affects the role of mPXR agonist PCN in alleviating sepsis-induced liver injury by regulating YAP activation.

Gut microbiota affects the role of mPXR agonist PCN in alleviating sepsis-induced liver injury by regulating YAP activation.

Journal: International immunopharmacology

Published: October 09, 2025

Constitutive androstane receptor activation modulates YAP expression and activity through ubiquitination and sumoylation.

Constitutive androstane receptor activation modulates YAP expression and activity through ubiquitination and sumoylation.

Journal: Toxicology letters

Published: April 23, 2025

Development and Validation of a HPLC-MS/MS Method for the Determination of Compound 13b in Rat Plasma and Its Application to a Pharmacokinetic Study.

Development and Validation of a HPLC-MS/MS Method for the Determination of Compound 13b in Rat Plasma and Its Application to a Pharmacokinetic Study.

Journal: Biomedical chromatography : BMC

Published: January 22, 2025

Pregnane X receptor alleviates sepsis-induced liver injury through activation of yes-associated protein in mice.

Pregnane X receptor alleviates sepsis-induced liver injury through activation of yes-associated protein in mice.

Journal: Acta pharmacologica Sinica

Published: October 15, 2024

Pregnane X receptor activation promotes hematopoiesis during liver regeneration by inducing proliferation of hematopoietic stem and progenitor cells in mice.

Pregnane X receptor activation promotes hematopoiesis during liver regeneration by inducing proliferation of hematopoietic stem and progenitor cells in mice.

Journal: Pharmacological research

Published: August 06, 2024

Schisandrol B alleviates depression-like behavior in mice by regulating bile acid homeostasis in the brain-liver-gut axis via the pregnane X receptor.

Schisandrol B alleviates depression-like behavior in mice by regulating bile acid homeostasis in the brain-liver-gut axis via the pregnane X receptor.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: August 03, 2024

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats.

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats.

Journal: Basic & clinical pharmacology & toxicology

Published: February 07, 2024

Potential herb‒drug interactions between anti-COVID-19 drugs and traditional Chinese medicine.

Potential herb‒drug interactions between anti-COVID-19 drugs and traditional Chinese medicine.

Journal: Acta pharmaceutica Sinica. B

Published: January 27, 2023

In Vivo CRISPR/Cas9-Mediated Genome Editing Mitigates Photoreceptor Degeneration in a Mouse Model of X-Linked Retinitis Pigmentosa.

In Vivo CRISPR/Cas9-Mediated Genome Editing Mitigates Photoreceptor Degeneration in a Mouse Model of X-Linked Retinitis Pigmentosa.

Journal: Investigative ophthalmology & visual science

Published: April 25, 2020

Mutation of TWNK Gene Is One of the Reasons of Runting and Stunting Syndrome Characterized by mtDNA Depletion in Sex-Linked Dwarf Chicken.

Mutation of TWNK Gene Is One of the Reasons of Runting and Stunting Syndrome Characterized by mtDNA Depletion in Sex-Linked Dwarf Chicken.

Journal: Frontiers in cell and developmental biology

Published: February 14, 2020

Growth Hormone Receptor Gene is Essential for Chicken Mitochondrial Function In Vivo and In Vitro.

Growth Hormone Receptor Gene is Essential for Chicken Mitochondrial Function In Vivo and In Vitro.

Journal: International journal of molecular sciences

Published: March 07, 2019

Runting and Stunting Syndrome Is Associated With Mitochondrial Dysfunction in Sex-Linked Dwarf Chicken.

Runting and Stunting Syndrome Is Associated With Mitochondrial Dysfunction in Sex-Linked Dwarf Chicken.

Journal: Frontiers in genetics

Published: December 16, 2018

Showing 1-12 of 13

Last Updated: 09/26/2026