Shuyi Zeng

Key Laboratory For The Genetics Of Developmental And Neuropsychiatric Disorders
Shanghai, 200030, China

Last Updated: 09/26/2026

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Found 8 publications

TPPP/p25 amyloid seeding activity as a specific biomarker for multiple system atrophy.

TPPP/p25 amyloid seeding activity as a specific biomarker for multiple system atrophy.

Journal: Cell
Published: August 01, 2025

A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson's disease model.

A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson's disease model.

Journal: Cell reports
Published: June 25, 2025

Design of Ig-like binders targeting α-synuclein fibril for mitigating its pathological activities.

Design of Ig-like binders targeting α-synuclein fibril for mitigating its pathological activities.

Journal: Nature communications
Published: September 19, 2024

Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures.

Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures.

Journal: Nature communications
Published: July 19, 2023

Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology.

Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology.

Journal: eLife
Published: May 02, 2022

Interaction of RAGE with α-synuclein fibrils mediates inflammatory response of microglia.

Interaction of RAGE with α-synuclein fibrils mediates inflammatory response of microglia.

Journal: Cell reports
Published: February 11, 2022

Biochemical and biophysical characterization of pathological aggregation of amyloid proteins.

Biochemical and biophysical characterization of pathological aggregation of amyloid proteins.

Journal: Biophysics reports
Published: July 30, 2021

Cellular and animal models to investigate pathogenesis of amyloid aggregation in neurodegenerative diseases.

Cellular and animal models to investigate pathogenesis of amyloid aggregation in neurodegenerative diseases.

Journal: Biophysics reports
Published: July 30, 2021
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Last Updated: 09/26/2026