Si Wu

19A Yuquan Road
Shijingshan, 100049, China

Last Updated: 09/26/2026

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Found 33 publications

Pathological Mutation E46K Acts as an Electrostatic Switch to Increase Distant Interdomain Interactions and Promote α‑Synuclein Phase Separation.

Pathological Mutation E46K Acts as an Electrostatic Switch to Increase Distant Interdomain Interactions and Promote α‑Synuclein Phase Separation.

Journal: JACS Au

Published: April 22, 2026

Reversibility and β-sheet formation are decoupled in tau condensate aging.

Reversibility and β-sheet formation are decoupled in tau condensate aging.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 13, 2026

NPM1 Undergoes Salt-Dependent Reentrant Phase Separation Driven by IDR Conformational Plasticity and Electrostatic Crosstalk.

NPM1 Undergoes Salt-Dependent Reentrant Phase Separation Driven by IDR Conformational Plasticity and Electrostatic Crosstalk.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: November 25, 2025

Exploring the effects of macromolecular crowding on the conformation and NuMA binding of 4.1G-CTD.

Exploring the effects of macromolecular crowding on the conformation and NuMA binding of 4.1G-CTD.

Journal: Physical chemistry chemical physics : PCCP

Published: July 29, 2025

Dissecting the Molecular Determinants of α-synuclein Phase Separation and Condensate Aging: The Pivotal Role of β-Sheet-Rich Motifs.

Dissecting the Molecular Determinants of α-synuclein Phase Separation and Condensate Aging: The Pivotal Role of β-Sheet-Rich Motifs.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: June 23, 2025

Direct Observation of the Conformational Transitions in Tau and Their Correlation with Phase Behavior.

Direct Observation of the Conformational Transitions in Tau and Their Correlation with Phase Behavior.

Journal: JACS Au

Published: May 18, 2025

Structural basis for the dynamic conformations of AP-4 and its association with ARF1.

Structural basis for the dynamic conformations of AP-4 and its association with ARF1.

Journal: Nature communications

Published: April 17, 2025

Single-molecule study of the dynamics of the molecular chaperone Hsp70 during the functional cycle.

Single-molecule study of the dynamics of the molecular chaperone Hsp70 during the functional cycle.

Journal: Biochemical Society transactions

Published: January 05, 2024

Interaction between huntingtin exon 1 and HEAT repeat structure probed by chimeric model proteins.

Interaction between huntingtin exon 1 and HEAT repeat structure probed by chimeric model proteins.

Journal: Protein science : a publication of the Protein Society

Published: June 29, 2023

Reversible Redox-Dependent Conformational Switch of the C-Terminal α-Helical Lid of Human Hsp70 Observed by In-Cell NMR.

Reversible Redox-Dependent Conformational Switch of the C-Terminal α-Helical Lid of Human Hsp70 Observed by In-Cell NMR.

Journal: ACS chemical biology

Published: December 16, 2022

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology.

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology.

Journal: Nature communications

Published: November 18, 2022

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid-liquid phase separation.

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid-liquid phase separation.

Journal: Essays in biochemistry

Published: September 20, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026