Siddharth Gusain

Dr. B. R. Ambedkar Centre For Biomedical Research
New Delhi, DL 110007, India

Last Updated: 09/26/2026

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Found 9 publications

Development of carbazole-based molecules for inhibition of mutant hSOD1 protein aggregation in Amyotrophic Lateral Sclerosis.

Development of carbazole-based molecules for inhibition of mutant hSOD1 protein aggregation in Amyotrophic Lateral Sclerosis.

Journal: Bioorganic & medicinal chemistry

Published: December 01, 2024

Synthesis, characterisation of ZnO@PDA@Ag nanocomposite: Mechanistic interaction with BSA, photodegradation activity & in vitro cytotoxicity assay on H1299 lung cancer cell line.

Synthesis, characterisation of ZnO@PDA@Ag nanocomposite: Mechanistic interaction with BSA, photodegradation activity & in vitro cytotoxicity assay on H1299 lung cancer cell line.

Journal: International journal of biological macromolecules

Published: May 22, 2024

Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.

Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: January 02, 2024

Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's disease.

Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's disease.

Journal: RSC advances

Published: January 21, 2020

Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation.

Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation.

Journal: Bioorganic chemistry

Published: September 23, 2019

A multifunctional therapeutic approach: Synthesis, biological evaluation, crystal structure and molecular docking of diversified 1H-pyrazolo[3,4-b]pyridine derivatives against Alzheimer's disease.

A multifunctional therapeutic approach: Synthesis, biological evaluation, crystal structure and molecular docking of diversified 1H-pyrazolo[3,4-b]pyridine derivatives against Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: March 05, 2019

Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents.

Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents.

Journal: Bioorganic & medicinal chemistry

Published: February 08, 2019

New amyloid beta-disaggregating agents: synthesis, pharmacological evaluation, crystal structure and molecular docking of N-(4-((7-chloroquinolin-4-yl)oxy)-3-ethoxybenzyl)amines.

New amyloid beta-disaggregating agents: synthesis, pharmacological evaluation, crystal structure and molecular docking of N-(4-((7-chloroquinolin-4-yl)oxy)-3-ethoxybenzyl)amines.

Journal: MedChemComm

Published: June 23, 2018

Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells.

Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells.

Journal: Pharmacological reports : PR

Published: September 09, 2016

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Last Updated: 09/26/2026