Sieger Leenstra
Rotterdam, ZH, Netherlands
Last Updated: 09/26/2026
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Found 52 publications
Epigenetic evolution of isocitrate dehydrogenase-wildtype glioblastomas.
Journal: Neuro-oncology
Published: August 28, 2025
Cut the fat: targeting cholesterol and lipid metabolism in glioblastoma.
Journal: Cell death & disease
Published: January 20, 2025
A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: October 25, 2024
BMP4 and Temozolomide Synergize in the Majority of Patient-Derived Glioblastoma Cultures.
Journal: International journal of molecular sciences
Published: August 16, 2024
Optimized culturing yields high success rates and preserves molecular heterogeneity, enabling personalized screening for high-grade gliomas.
Journal: NPJ precision oncology
Published: November 25, 2023
Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells.
Journal: International journal of molecular sciences
Published: September 06, 2023
Cognition and health-related quality of life in long-term survivors of high-grade glioma: an interactive perspective from patient and caregiver.
Journal: Acta neurochirurgica
Published: August 19, 2023
Investigating chromosomal instability in long-term survivors with glioblastoma and grade 4 astrocytoma.
Journal: Frontiers in oncology
Published: May 06, 2023
Comparative analysis of deeply phenotyped GBM cohorts of 'short-term' and 'long-term' survivors.
Journal: Journal of neuro-oncology
Published: April 18, 2023
Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
Journal: Molecular cancer
Published: March 10, 2023
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
Journal: British journal of cancer
Published: December 08, 2022
Last Updated: 09/26/2026