Siliang Chen

610041, PR China
Puerto Rico

Last Updated: 09/26/2026

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Found 12 publications

Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.

Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.

Journal: Materials today. Bio

Published: July 21, 2025

Discovery of first-in-class highly selective TRPV1 antagonists with dual analgesic and hypoglycemic effects.

Discovery of first-in-class highly selective TRPV1 antagonists with dual analgesic and hypoglycemic effects.

Journal: Bioorganic & medicinal chemistry

Published: March 03, 2024

Discovery of LH10, a novel fexaramine-based FXR agonist for the treatment of liver disease.

Discovery of LH10, a novel fexaramine-based FXR agonist for the treatment of liver disease.

Journal: Bioorganic chemistry

Published: November 03, 2023

Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis.

Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis.

Journal: Biochemical pharmacology

Published: June 24, 2023

Discovery of the First-in-Class Intestinal Restricted FXR and FABP1 Dual Modulator ZLY28 for the Treatment of Nonalcoholic Fatty Liver Disease.

Discovery of the First-in-Class Intestinal Restricted FXR and FABP1 Dual Modulator ZLY28 for the Treatment of Nonalcoholic Fatty Liver Disease.

Journal: Journal of medicinal chemistry

Published: April 20, 2023

Design, synthesis, and biological studies of novel sulfonamide derivatives as farnesoid X receptor agonists.

Design, synthesis, and biological studies of novel sulfonamide derivatives as farnesoid X receptor agonists.

Journal: European journal of medicinal chemistry

Published: March 21, 2023

Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea.

Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea.

Journal: Bioorganic chemistry

Published: February 16, 2023

Design, synthesis, and biological studies of dual URAT1 inhibitor and FXR agonist based on benzbromarone.

Design, synthesis, and biological studies of dual URAT1 inhibitor and FXR agonist based on benzbromarone.

Journal: Bioorganic & medicinal chemistry

Published: August 23, 2022

Discovery of a structurally novel, potent, and once-weekly free fatty acid receptor 1 agonist for the treatment of diabetes.

Discovery of a structurally novel, potent, and once-weekly free fatty acid receptor 1 agonist for the treatment of diabetes.

Journal: European journal of medicinal chemistry

Published: June 28, 2022

Anti-CASPR2 antibody associated encephalitis with anosmia and demyelinating pseudotumor: A case report.

Anti-CASPR2 antibody associated encephalitis with anosmia and demyelinating pseudotumor: A case report.

Journal: Journal of neuroimmunology

Published: July 23, 2020

Community-based rehabilitation service in Chengdu, Southwest China: a cross-sectional general survey.

Community-based rehabilitation service in Chengdu, Southwest China: a cross-sectional general survey.

Journal: BMC health services research

Published: November 13, 2019

Identification of crucial genes in abdominal aortic aneurysm by WGCNA.

Identification of crucial genes in abdominal aortic aneurysm by WGCNA.

Journal: PeerJ

Published: May 21, 2019

Showing 1-12 of 12

Last Updated: 09/26/2026