Silvana Libertini

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 20 publications

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

Journal: Gene therapy

Published: November 10, 2025

Summary of Major Conclusions From the 8th International Workshop on Genotoxicity Testing (IWGT), Ottawa, Canada.

Summary of Major Conclusions From the 8th International Workshop on Genotoxicity Testing (IWGT), Ottawa, Canada.

Journal: Environmental and molecular mutagenesis

Published: September 17, 2025

Long-read target enrichment sequencing for rAAV integration site analysis in engineered clones with targeted viral insertion.

Long-read target enrichment sequencing for rAAV integration site analysis in engineered clones with targeted viral insertion.

Journal: Molecular therapy. Nucleic acids

Published: August 28, 2025

SACF and GILA assays on AML12 cells show limited predictive value for mouse liver genotoxicity.

SACF and GILA assays on AML12 cells show limited predictive value for mouse liver genotoxicity.

Journal: Toxicology and applied pharmacology

Published: June 27, 2025

Isolated oral CD30+/CD4+ CAR+ T cell lymphoma in long-term remission after radiotherapy.

Isolated oral CD30+/CD4+ CAR+ T cell lymphoma in long-term remission after radiotherapy.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: June 04, 2025

Aggressive Lymphoma after CD19 CAR T-Cell Therapy.

Aggressive Lymphoma after CD19 CAR T-Cell Therapy.

Journal: The New England journal of medicine

Published: November 26, 2024

Pilocytic astrocytoma in a child with spinal muscular atrophy treated with onasemnogene abeparvovec.

Pilocytic astrocytoma in a child with spinal muscular atrophy treated with onasemnogene abeparvovec.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: November 06, 2024

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Journal: Human gene therapy

Published: July 25, 2024

Genotoxicity evaluation of gene therapies: A report from the International Workshop on Genotoxicity Testing (IWGT) 2022.

Genotoxicity evaluation of gene therapies: A report from the International Workshop on Genotoxicity Testing (IWGT) 2022.

Journal: Environmental and molecular mutagenesis

Published: July 24, 2024

Detection of residual pluripotent stem cells in cell therapy products utilizing droplet digital PCR: an international multisite evaluation study.

Detection of residual pluripotent stem cells in cell therapy products utilizing droplet digital PCR: an international multisite evaluation study.

Journal: Stem cells translational medicine

Published: February 28, 2024

PET-based tracking of CAR T cells and viral gene transfer using a cell surface reporter that binds to lanthanide complexes.

PET-based tracking of CAR T cells and viral gene transfer using a cell surface reporter that binds to lanthanide complexes.

Journal: Nature biomedical engineering

Published: July 31, 2023

Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec.

Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: June 07, 2023

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Last Updated: 09/26/2026