Silvia Grottelli

Perugia, 06132, Italy

Last Updated: 09/26/2026

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Found 24 publications

A molecular perspective on dimethylarginine dimethylaminohydrolases structure and function.

A molecular perspective on dimethylarginine dimethylaminohydrolases structure and function.

Journal: The Biochemical journal

Published: February 23, 2026

Nanobodies as therapies for loss-of-function misfolding diseases: the example of Primary Hyperoxaluria Type 1.

Nanobodies as therapies for loss-of-function misfolding diseases: the example of Primary Hyperoxaluria Type 1.

Journal: International journal of biological macromolecules

Published: May 09, 2025

Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1.

Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1.

Journal: Journal of chemical information and modeling

Published: August 23, 2024

Impact of Enniatin and Deoxynivalenol Co-Occurrence on Plant, Microbial, Insect, Animal and Human Systems: Current Knowledge and Future Perspectives.

Impact of Enniatin and Deoxynivalenol Co-Occurrence on Plant, Microbial, Insect, Animal and Human Systems: Current Knowledge and Future Perspectives.

Journal: Toxins

Published: March 09, 2023

A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase.

A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase.

Journal: Nature communications

Published: October 05, 2022

Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1.

Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1.

Journal: Journal of medicinal chemistry

Published: July 13, 2022

CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1.

CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1.

Journal: Biochimie

Published: December 22, 2021

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase.

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase.

Journal: Protein science : a publication of the Protein Society

Published: November 25, 2021

Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach.

Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach.

Journal: Frontiers in bioscience (Landmark edition)

Published: August 28, 2021

Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina.

Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina.

Journal: Frontiers in molecular biosciences

Published: April 14, 2021

Dimerization Drives Proper Folding of Human Alanine:Glyoxylate Aminotransferase But Is Dispensable for Peroxisomal Targeting.

Dimerization Drives Proper Folding of Human Alanine:Glyoxylate Aminotransferase But Is Dispensable for Peroxisomal Targeting.

Journal: Journal of personalized medicine

Published: March 07, 2021

Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells.

Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells.

Journal: Molecules (Basel, Switzerland)

Published: April 22, 2020

Showing 1-12 of 24

Last Updated: 09/26/2026