Silvia Gutierrez-Ortega

Madrid, MD 28040, Spain

Last Updated: 09/26/2026

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Found 37 publications

ICMT supports BRAFV600E-driven tumor growth by membrane targeting of the CAAX protein INPP5E.

ICMT supports BRAFV600E-driven tumor growth by membrane targeting of the CAAX protein INPP5E.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 13, 2026

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria.

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 31, 2025

The development and therapeutic potential of classical and next-generation cannabinoid ligands.

The development and therapeutic potential of classical and next-generation cannabinoid ligands.

Journal: Pharmacological research

Published: June 22, 2025

Chemical probes for the identification of the molecular targets of honokiol.

Chemical probes for the identification of the molecular targets of honokiol.

Journal: European journal of medicinal chemistry

Published: August 01, 2024

Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activity.

Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activity.

Journal: Nature chemistry

Published: October 06, 2023

A new fluorescent probe for the visualization of progerin.

A new fluorescent probe for the visualization of progerin.

Journal: Bioorganic chemistry

Published: September 25, 2023

New Pharmacological Approaches for Rare Diseases.

New Pharmacological Approaches for Rare Diseases.

Journal: International journal of molecular sciences

Published: April 02, 2023

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice.

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice.

Journal: Journal of medicinal chemistry

Published: August 10, 2022

New Trends in Aging Drug Discovery.

New Trends in Aging Drug Discovery.

Journal: Biomedicines

Published: July 30, 2022

Small-Molecule Therapeutic Perspectives for the Treatment of Progeria.

Small-Molecule Therapeutic Perspectives for the Treatment of Progeria.

Journal: International journal of molecular sciences

Published: June 07, 2021

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.

Journal: ACS central science

Published: December 21, 2020

Serum endocannabinoid levels in suicide attempters: A pilot study.

Serum endocannabinoid levels in suicide attempters: A pilot study.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

Published: December 31, 2019

Showing 1-12 of 37

Last Updated: 09/26/2026