Silvio Holzner

Vienna, Austria

Last Updated: 09/26/2026

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Found 12 publications

Off-targets of BRAF inhibitors disrupt endothelial signaling and vascular barrier function.

Off-targets of BRAF inhibitors disrupt endothelial signaling and vascular barrier function.

Journal: Life science alliance

Published: February 22, 2024

Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells.

Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells.

Journal: Journal of cell science

Published: February 15, 2021

Inhibition of p38/MK2 Signaling Prevents Vascular Invasion of Melanoma.

Inhibition of p38/MK2 Signaling Prevents Vascular Invasion of Melanoma.

Journal: The Journal of investigative dermatology

Published: April 11, 2019

Intravasation of SW620 colon cancer cell spheroids through the blood endothelial barrier is inhibited by clinical drugs and flavonoids in vitro.

Intravasation of SW620 colon cancer cell spheroids through the blood endothelial barrier is inhibited by clinical drugs and flavonoids in vitro.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: September 05, 2017

Fenofibrate inhibits tumour intravasation by several independent mechanisms in a 3-dimensional co-culture model.

Fenofibrate inhibits tumour intravasation by several independent mechanisms in a 3-dimensional co-culture model.

Journal: International journal of oncology

Published: December 03, 2016

Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells.

Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells.

Journal: Scientific reports

Published: October 13, 2016

Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in vitro.

Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in vitro.

Journal: Oncology reports

Published: May 04, 2016

12(S)-HETE increases intracellular Ca(2+) in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply.

12(S)-HETE increases intracellular Ca(2+) in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply.

Journal: Cancer letters

Published: April 26, 2016

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.

Journal: Cellular and molecular life sciences : CMLS

Published: March 22, 2016

NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro.

NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro.

Journal: Oncotarget

Published: June 16, 2015

Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro.

Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro.

Journal: Human molecular genetics

Published: February 04, 2015

A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.

A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.

Journal: Mutation research

Published: December 04, 2014

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Last Updated: 09/26/2026