Simon E. Ward

Park Place
Cardiff, WLS, United Kingdom

Last Updated: 09/26/2026

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Found 72 publications

Tetrahydropyrazolopyridinones as a Novel Class of Potent and Highly Selective LIMK Inhibitors.

Tetrahydropyrazolopyridinones as a Novel Class of Potent and Highly Selective LIMK Inhibitors.

Journal: Journal of medicinal chemistry

Published: August 06, 2025

High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1.

High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1.

Journal: Structure (London, England : 1993)

Published: January 21, 2025

The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells.

The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells.

Journal: Nature communications

Published: January 14, 2025

Discovery of MDI-114215: A Potent and Selective LIMK Inhibitor To Treat Fragile X Syndrome.

Discovery of MDI-114215: A Potent and Selective LIMK Inhibitor To Treat Fragile X Syndrome.

Journal: Journal of medicinal chemistry

Published: December 23, 2024

How Do Gepotidacin and Zoliflodacin Stabilize DNA-Cleavage Complexes with Bacterial Type IIA Topoisomerases? 2. A Single Moving Metal Mechanism.

How Do Gepotidacin and Zoliflodacin Stabilize DNA-Cleavage Complexes with Bacterial Type IIA Topoisomerases? 2. A Single Moving Metal Mechanism.

Journal: International journal of molecular sciences

Published: November 12, 2024

Journal of Medicinal Chemistry Collection: Drug Discovery in the UK.

Journal of Medicinal Chemistry Collection: Drug Discovery in the UK.

Journal: Journal of medicinal chemistry

Published: October 17, 2024

Fingerprints of supersymmetric spin and charge dynamics observed by inelastic neutron scattering.

Fingerprints of supersymmetric spin and charge dynamics observed by inelastic neutron scattering.

Journal: Nature communications

Published: September 05, 2024

How Do Gepotidacin and Zoliflodacin Stabilize DNA Cleavage Complexes with Bacterial Type IIA Topoisomerases? 1. Experimental Definition of Metal Binding Sites.

How Do Gepotidacin and Zoliflodacin Stabilize DNA Cleavage Complexes with Bacterial Type IIA Topoisomerases? 1. Experimental Definition of Metal Binding Sites.

Journal: International journal of molecular sciences

Published: September 04, 2024

Beware of N-Benzoyloxybenzamides.

Beware of N-Benzoyloxybenzamides.

Journal: Molecules (Basel, Switzerland)

Published: September 02, 2024

Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases.

Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases.

Journal: European journal of medicinal chemistry

Published: January 06, 2024

Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives.

Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives.

Journal: Frontiers in cell and developmental biology

Published: June 25, 2023

Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues.

Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues.

Journal: iScience

Published: June 16, 2023

Showing 1-12 of 72

Last Updated: 09/26/2026