Simon G. Lillico

Edinburgh, SCT EH259RG, United Kingdom

Last Updated: 09/26/2026

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Found 44 publications

DNAJC14 gene-edited pigs are resistant to classical pestiviruses.

DNAJC14 gene-edited pigs are resistant to classical pestiviruses.

Journal: Trends in biotechnology

Published: May 15, 2025

AAV-delivered PPT1 provides long-term neurological benefits in CLN1 mice and achieves therapeutic levels in sheep brain.

AAV-delivered PPT1 provides long-term neurological benefits in CLN1 mice and achieves therapeutic levels in sheep brain.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 04, 2025

Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.

Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.

Journal: Nature communications

Published: April 03, 2024

Maternal α-casein deficiency extends the lifespan of offspring and programmes their body composition.

Maternal α-casein deficiency extends the lifespan of offspring and programmes their body composition.

Journal: GeroScience

Published: February 17, 2024

Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen.

Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen.

Journal: Viruses

Published: December 08, 2023

Site specific insertion of a transgene into the murine α-casein (CSN1S1) gene results in the predictable expression of a recombinant protein in milk.

Site specific insertion of a transgene into the murine α-casein (CSN1S1) gene results in the predictable expression of a recombinant protein in milk.

Journal: Biotechnology journal

Published: June 13, 2023

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen.

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen.

Journal: PLoS pathogens

Published: November 27, 2022

Generation of sheep with defined FecBB and TBXT mutations and porcine blastocysts with KCNJ5G151R/+ mutation using prime editing.

Generation of sheep with defined FecBB and TBXT mutations and porcine blastocysts with KCNJ5G151R/+ mutation using prime editing.

Journal: BMC genomics

Published: November 14, 2022

Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment.

Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment.

Journal: Cells

Published: July 25, 2022

Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.

Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.

Journal: The Journal of clinical investigation

Published: June 29, 2022

Regulatory frameworks can facilitate or hinder the potential for genome editing to contribute to sustainable agricultural development.

Regulatory frameworks can facilitate or hinder the potential for genome editing to contribute to sustainable agricultural development.

Journal: Frontiers in bioengineering and biotechnology

Published: June 01, 2022

Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors.

Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors.

Journal: BMC genomics

Published: March 23, 2021

Showing 1-12 of 44

Last Updated: 09/26/2026