Simon Gutbier

Konstanz, BW 78464, Germany

Last Updated: 09/26/2026

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Found 31 publications

Development and Characterization of a Novel α-Synuclein-PEST H4 Cell Line for Enhanced Drug Screening in α-Synucleinopathies.

Development and Characterization of a Novel α-Synuclein-PEST H4 Cell Line for Enhanced Drug Screening in α-Synucleinopathies.

Journal: International journal of molecular sciences

Published: June 20, 2025

A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors.

A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors.

Journal: Glia

Published: June 04, 2024

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Discovery of Orally Available and Brain Penetrant AEP Inhibitors.

Journal: Journal of medicinal chemistry

Published: December 13, 2023

Definition of the Neurotoxicity-Associated Metabolic Signature Triggered by Berberine and Other Respiratory Chain Inhibitors.

Definition of the Neurotoxicity-Associated Metabolic Signature Triggered by Berberine and Other Respiratory Chain Inhibitors.

Journal: Antioxidants (Basel, Switzerland)

Published: October 24, 2023

Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration.

Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration.

Journal: Environment international

Published: August 15, 2023

Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons.

Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons.

Journal: Antioxidants (Basel, Switzerland)

Published: December 08, 2022

A Novel Mitochondria-Targeting Iron Chelator Neuroprotects Multimodally via HIF-1 Modulation Against a Mitochondrial Toxin in a Dopaminergic Cell Model of Parkinson's Disease.

A Novel Mitochondria-Targeting Iron Chelator Neuroprotects Multimodally via HIF-1 Modulation Against a Mitochondrial Toxin in a Dopaminergic Cell Model of Parkinson's Disease.

Journal: Molecular neurobiology

Published: August 05, 2022

Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity.

Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity.

Journal: Cells

Published: December 23, 2021

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity.

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity.

Journal: Frontiers in immunology

Published: March 23, 2021

Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages.

Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages.

Journal: Cell death & disease

Published: January 19, 2021

Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia.

Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia.

Journal: Frontiers in immunology

Published: October 15, 2020

Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.

Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.

Journal: International journal of molecular sciences

Published: June 05, 2020

Showing 1-12 of 31

Last Updated: 09/26/2026