Simon J. Boulton
Midland Road
London, ENG, United Kingdom
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 111 publications
H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomas.
Journal: bioRxiv : the preprint server for biology
Published: May 25, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: February 06, 2026
Cryo-electron microscopic visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2.
Journal: Science (New York, N.Y.)
Published: November 06, 2025
Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity.
Journal: Nature structural & molecular biology
Published: September 08, 2025
Hypoxic stress is an early pathogenic event in human VCP-mutant ALS astrocytes.
Journal: Stem cell reports
Published: June 02, 2025
RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress.
Journal: Nature cell biology
Published: January 12, 2025
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics.
Journal: Nature communications
Published: July 26, 2024
Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-based Reporter Assays.
Journal: Journal of visualized experiments : JoVE
Published: July 01, 2024
EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.
Journal: Nature communications
Published: June 26, 2024
Extraordinary collateral mutagenesis induced by CX-5461.
Journal: Nature genetics
Published: December 21, 2023
Last Updated: 09/26/2026