Simon Lam

Denmark Hill
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 28 publications

Targeting epigenetic regulators induces transcription-replication conflicts to overcome ATR inhibitor resistance.

Targeting epigenetic regulators induces transcription-replication conflicts to overcome ATR inhibitor resistance.

Journal: Nucleic acids research

Published: December 30, 2025

Cell-stereotyped DNA repair outcomes are widespread during genome editing.

Cell-stereotyped DNA repair outcomes are widespread during genome editing.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

Adult presentation of a PLAGL2-amplified neuroepithelial tumor mimicking glioblastoma: broadening the spectrum of a proposed entity.

Adult presentation of a PLAGL2-amplified neuroepithelial tumor mimicking glioblastoma: broadening the spectrum of a proposed entity.

Journal: Acta neuropathologica communications

Published: October 02, 2025

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay.

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay.

Journal: EMBO molecular medicine

Published: May 06, 2025

WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2.

WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2.

Journal: Nature communications

Published: March 10, 2025

RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response.

RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response.

Journal: Molecular cell

Published: March 03, 2025

USP37 prevents premature disassembly of stressed replisomes by TRAIP.

USP37 prevents premature disassembly of stressed replisomes by TRAIP.

Journal: Nature communications

Published: August 30, 2024

Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts.

Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts.

Journal: Current biology : CB

Published: July 05, 2024

Retraction notice to "Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases" [Life Sci. 314 (2023) 121325].

Retraction notice to "Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases" [Life Sci. 314 (2023) 121325].

Journal: Life sciences

Published: May 18, 2024

KLF5 loss sensitizes cells to ATR inhibition and is synthetic lethal with ARID1A deficiency.

KLF5 loss sensitizes cells to ATR inhibition and is synthetic lethal with ARID1A deficiency.

Journal: Nature communications

Published: April 22, 2024

Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens.

Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens.

Journal: Genome medicine

Published: April 03, 2024

Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial.

Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial.

Journal: Brain communications

Published: November 02, 2023

Showing 1-12 of 28

Last Updated: 09/26/2026