Simon Linder

Amsterdam, NH, Netherlands

Last Updated: 09/26/2026

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Found 25 publications

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.

Journal: Science advances
Published: September 03, 2025

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

Journal: Science (New York, N.Y.)
Published: July 03, 2025

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer.

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 06, 2025

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

Journal: Communications biology
Published: January 14, 2025

Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes.

Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes.

Journal: Nucleic acids research
Published: August 08, 2024

Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.

Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.

Journal: Cancer discovery
Published: April 23, 2024

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.

Journal: The Journal of clinical investigation
Published: September 29, 2023

Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer.

Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer.

Journal: Cancers
Published: April 19, 2023

Compartmentalization of androgen receptors at endogenous genes in living cells.

Compartmentalization of androgen receptors at endogenous genes in living cells.

Journal: Nucleic acids research
Published: April 14, 2023

Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.

Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.

Journal: Cancer discovery
Published: March 21, 2023

Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients.

Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients.

Journal: medRxiv : the preprint server for health sciences
Published: March 03, 2023

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

Journal: Cell reports. Medicine
Published: February 24, 2023
Showing 1-12 of 25

Last Updated: 09/26/2026