Simon P. Dearden
Oncology R&D
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 20 publications
Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes.
Journal: Breast cancer research and treatment
Published: June 01, 2023
The landscape of BRCA1 and BRCA2 large rearrangements in an international cohort of over 20 000 ovarian tumors identified using next-generation sequencing.
Journal: Genes, chromosomes & cancer
Published: November 03, 2022
Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: March 23, 2022
Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: November 03, 2021
Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial.
Journal: Gynecologic oncology
Published: July 12, 2021
Analysis of mutation status and homologous recombination deficiency in tumors of patients with germline BRCA1 or BRCA2 mutations and metastatic breast cancer: OlympiAD.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology
Published: April 21, 2021
Tissue and Plasma EGFR Mutation Analysis in the FLAURA Trial: Osimertinib versus Comparator EGFR Tyrosine Kinase Inhibitor as First-Line Treatment in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: April 05, 2019
Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy.
Journal: Scientific reports
Published: January 03, 2019
EGFR Mutation Analysis for Prospective Patient Selection in Two Phase II Registration Studies of Osimertinib.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Published: February 22, 2017
EGFR T790M mutation testing within the osimertinib AURA Phase I study.
Journal: Lung cancer (Amsterdam, Netherlands)
Published: December 06, 2016
EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291.
Journal: Lung cancer (Amsterdam, Netherlands)
Published: August 13, 2015
Last Updated: 09/26/2026