Simon P. Keam

305 Grattan St
Melbourne, VIC 3000, Australia

Last Updated: 09/26/2026

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Found 36 publications

βc receptor antagonism mitigates sarcoidosis granuloma formation by targeting inflammatory signals and aberrant lipid metabolism.

βc receptor antagonism mitigates sarcoidosis granuloma formation by targeting inflammatory signals and aberrant lipid metabolism.

Journal: Frontiers in immunology

Published: October 27, 2025

Neoadjuvant lutetium PSMA, the TIME and immune response in high-risk localized prostate cancer.

Neoadjuvant lutetium PSMA, the TIME and immune response in high-risk localized prostate cancer.

Journal: Nature reviews. Urology

Published: June 21, 2024

Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade.

Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade.

Journal: The Journal of allergy and clinical immunology

Published: March 25, 2023

Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status.

Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status.

Journal: Cancers

Published: July 12, 2022

Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss.

Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss.

Journal: Cell death & disease

Published: May 26, 2022

Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments.

Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments.

Journal: Nature communications

Published: May 05, 2022

Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes.

Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes.

Journal: Journal for immunotherapy of cancer

Published: April 14, 2022

Tissue-resident memory T cells from a metastatic vaginal melanoma patient are tumor-responsive T cells and increase after anti-PD-1 treatment.

Tissue-resident memory T cells from a metastatic vaginal melanoma patient are tumor-responsive T cells and increase after anti-PD-1 treatment.

Journal: Journal for immunotherapy of cancer

Published: April 05, 2022

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.

Journal: Haematologica

Published: October 04, 2021

Single-Cell Gene Expression, Clonality, and Feature Barcoding of Melanoma Tumor-Infiltrating Lymphocytes.

Single-Cell Gene Expression, Clonality, and Feature Barcoding of Melanoma Tumor-Infiltrating Lymphocytes.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: March 11, 2021

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression.

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression.

Journal: BMC cancer

Published: March 10, 2021

Regulatory T Cells Shape the Differential Impact of Radiation Dose-Fractionation Schedules on Host Innate and Adaptive Antitumor Immune Defenses.

Regulatory T Cells Shape the Differential Impact of Radiation Dose-Fractionation Schedules on Host Innate and Adaptive Antitumor Immune Defenses.

Journal: International journal of radiation oncology, biology, physics

Published: February 19, 2021

Showing 1-12 of 36

Last Updated: 09/26/2026