Simona Casini - Publications

Decreasing Microtubule Detyrosination Improves Cardiac Mechanics and Sodium Channel Function in Arrhythmogenic Cardiomyopathy.

Journal: Circulation. Arrhythmia and electrophysiology

Published: June 29, 2026

SGK1-inhibition restores cardiac repolarization in LQT2 rabbits and LQT3 mice by reducing late sodium current.

Journal: Pharmacological research

Published: February 16, 2026

Chronic Mexiletine Administration Increases Sodium Current in Non-Diseased Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Journal: Biomedicines

Published: May 15, 2024

Decreasing microtubule detyrosination modulates Nav1.5 subcellular distribution and restores sodium current in mdx cardiomyocytes.

Journal: Cardiovascular research

Published: August 02, 2023

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.

Journal: Science translational medicine

Published: March 22, 2023

Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Published: March 20, 2023

Gene- and variant-specific efficacy of serum/glucocorticoid-regulated kinase 1 inhibition in long QT syndrome types 1 and 2.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Published: February 18, 2023