Simona Iezzi
Rome, Italy
Last Updated: 09/26/2026
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Found 16 publications
AATF supports proliferation of glioblastoma cells by sustaining mitochondrial respiration through an NRF-1-dependent mechanism.
Journal: Cell death & disease
Published: June 27, 2025
Immunotherapy in melanoma: advances, pitfalls, and future perspectives.
Journal: Frontiers in molecular biosciences
Published: March 18, 2024
HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response.
Journal: Biochimica et biophysica acta. Molecular cell research
Published: May 18, 2023
AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation.
Journal: Frontiers in immunology
Published: March 22, 2023
CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity.
Journal: Journal of experimental & clinical cancer research : CR
Published: April 23, 2021
Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Journal: Nucleic acids research
Published: July 24, 2019
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.
Journal: EMBO reports
Published: July 20, 2017
Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.
Journal: Journal of experimental & clinical cancer research : CR
Published: January 12, 2017
Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.
Journal: Oncotarget
Published: April 29, 2016
Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins.
Journal: Frontiers in oncology
Published: October 07, 2015
Discovering Che-1/AATF: a new attractive target for cancer therapy.
Journal: Frontiers in genetics
Published: February 24, 2015
Last Updated: 09/26/2026