Simona Porcellini
Milan, 20132, Italy
Last Updated: 09/26/2026
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Found 11 publications
A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells.
Journal: Cell reports. Medicine
Published: March 22, 2024
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency.
Journal: Science translational medicine
Published: February 07, 2024
Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated in vitro and in vivo.
Journal: Molecular therapy. Methods & clinical development
Published: May 25, 2023
Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4+ T-cells for the treatment of Hyper IgM1.
Journal: The EMBO journal
Published: April 04, 2023
Characterization and Functional Analysis of CD44v6.CAR T Cells Endowed with a New Low-Affinity Nerve Growth Factor Receptor-Based Spacer.
Journal: Human gene therapy
Published: February 08, 2021
CAR T Cells Redirected to CD44v6 Control Tumor Growth in Lung and Ovary Adenocarcinoma Bearing Mice.
CAR T Cells Redirected to CD44v6 Control Tumor Growth in Lung and Ovary Adenocarcinoma Bearing Mice.
Journal: Frontiers in immunology
Published: September 11, 2019
Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling.
Journal: International journal of molecular sciences
Published: July 31, 2019
Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene.
Journal: Frontiers in immunology
Published: November 09, 2017
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms.
Journal: Oncoimmunology
Published: February 03, 2015
Anti-metastatic activity of the tumor vascular targeting agent NGR-TNF.
Journal: Clinical & experimental metastasis
Published: August 05, 2014
Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase.
Journal: Nucleic acids research
Published: March 15, 2014
Showing 1-11 of 11
Last Updated: 09/26/2026