Simone Hornemann

Zurich, ZH, Switzerland

Last Updated: 09/26/2026

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Found 44 publications

Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity.

Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity.

Journal: PLoS biology

Published: September 23, 2025

The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis.

The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis.

Journal: EMBO molecular medicine

Published: May 28, 2024

Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes.

Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes.

Journal: Nature biomedical engineering

Published: September 25, 2023

Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic.

Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic.

Journal: PloS one

Published: August 08, 2023

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Journal: iScience

Published: August 16, 2022

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.

Journal: The EMBO journal

Published: August 10, 2022

Concordance of cerebrospinal fluid real-time quaking-induced conversion across the European Creutzfeldt-Jakob Disease Surveillance Network.

Concordance of cerebrospinal fluid real-time quaking-induced conversion across the European Creutzfeldt-Jakob Disease Surveillance Network.

Journal: European journal of neurology

Published: March 30, 2022

A conformational switch controlling the toxicity of the prion protein.

A conformational switch controlling the toxicity of the prion protein.

Journal: Nature structural & molecular biology

Published: December 01, 2021

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.

Journal: Science advances

Published: November 24, 2021

Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.

Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.

Journal: PLoS pathogens

Published: September 28, 2021

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.

Journal: EMBO molecular medicine

Published: June 18, 2021

Mechanism of misfolding of the human prion protein revealed by a pathological mutation.

Mechanism of misfolding of the human prion protein revealed by a pathological mutation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 18, 2021

Showing 1-12 of 44

Last Updated: 09/26/2026