Simone I. Schulz

Wuppertal, NW, Germany

Last Updated: 09/26/2026

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Found 13 publications

Mass Balance Recovery, Absorption, Metabolism, and Excretion of Elinzanetant in Healthy Human Volunteers and in vitro Biotransformation.

Mass Balance Recovery, Absorption, Metabolism, and Excretion of Elinzanetant in Healthy Human Volunteers and in vitro Biotransformation.

Journal: European journal of drug metabolism and pharmacokinetics

Published: November 25, 2024

Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.

Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: September 18, 2023

Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.

Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.

Journal: Clinical pharmacology and therapeutics

Published: August 21, 2023

Metabolism and Disposition of the Novel Oral Factor XIa Inhibitor Asundexian in Rats and in Humans.

Metabolism and Disposition of the Novel Oral Factor XIa Inhibitor Asundexian in Rats and in Humans.

Journal: European journal of drug metabolism and pharmacokinetics

Published: June 06, 2023

In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites.

In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites.

Journal: Current drug metabolism

Published: April 28, 2023

Correction to "Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox".

Correction to "Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox".

Journal: Chemical research in toxicology

Published: April 18, 2023

Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.

Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.

Journal: Chemical research in toxicology

Published: October 09, 2022

Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.

Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.

Journal: Clinical pharmacology and therapeutics

Published: February 18, 2022

Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics.

Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics.

Journal: Journal of medicinal chemistry

Published: October 27, 2020

Drug-drug interaction of atazanavir on UGT1A1-mediated glucuronidation of molidustat in human.

Drug-drug interaction of atazanavir on UGT1A1-mediated glucuronidation of molidustat in human.

Journal: Basic & clinical pharmacology & toxicology

Published: July 03, 2020

Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile.

Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile.

Journal: Journal of medicinal chemistry

Published: November 21, 2019

Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure.

Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure.

Journal: European journal of medicinal chemistry

Published: September 27, 2018

Showing 1-12 of 13

Last Updated: 09/26/2026