Simone W. Denis

Amsterdam, NH, Netherlands

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 31 publications

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle.

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle.

Journal: Nature aging

Published: February 27, 2025

Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.

Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.

Journal: Scientific reports

Published: June 25, 2024

Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes.

Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes.

Journal: iScience

Published: June 24, 2024

Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay.

Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay.

Journal: Molecular genetics and metabolism

Published: May 29, 2024

Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS.

Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS.

Journal: FASEB bioAdvances

Published: April 10, 2024

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.

Journal: bioRxiv : the preprint server for biology

Published: February 14, 2024

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.

Journal: Scientific reports

Published: January 31, 2024

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise.

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise.

Journal: Nature aging

Published: December 23, 2022

Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis.

Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis.

Journal: Cells

Published: November 03, 2022

Altered lipid metabolism in synovial fibroblasts of individuals at risk of developing rheumatoid arthritis.

Altered lipid metabolism in synovial fibroblasts of individuals at risk of developing rheumatoid arthritis.

Journal: Journal of autoimmunity

Published: October 24, 2022

Neonatal Long-Chain 3-Ketoacyl-CoA Thiolase deficiency: Clinical-biochemical phenotype, sodium-D,L-3-hydroxybutyrate treatment experience and cardiac evaluation using speckle echocardiography.

Neonatal Long-Chain 3-Ketoacyl-CoA Thiolase deficiency: Clinical-biochemical phenotype, sodium-D,L-3-hydroxybutyrate treatment experience and cardiac evaluation using speckle echocardiography.

Journal: Molecular genetics and metabolism reports

Published: April 16, 2022

Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy.

Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy.

Journal: Journal of magnetic resonance imaging : JMRI

Published: December 02, 2020

Showing 1-12 of 31

Last Updated: 09/26/2026