Simonetta Sipione

Edmonton, AB, Canada

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 28 publications

Intracerebroventricular Administration of Gangliosides for In Vivo Functional Studies in Mice.

Intracerebroventricular Administration of Gangliosides for In Vivo Functional Studies in Mice.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 19, 2026

Gangliosides in the 21st century: therapeutic prospects for the brain and spine.

Gangliosides in the 21st century: therapeutic prospects for the brain and spine.

Journal: Frontiers in neurology

Published: February 03, 2026

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

Journal: Science advances

Published: September 17, 2025

Native PLGA nanoparticles attenuate disease pathology via multiple pathways in 5xFAD Alzheimer's model.

Native PLGA nanoparticles attenuate disease pathology via multiple pathways in 5xFAD Alzheimer's model.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: June 24, 2025

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

Journal: Pharmaceutics

Published: April 04, 2025

Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1.

Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1.

Journal: Journal of neuroinflammation

Published: March 07, 2023

Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.

Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.

Journal: Nature communications

Published: August 26, 2022

Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model.

Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model.

Journal: Stem cell reports

Published: March 14, 2022

In-Cell Labeling Coupled to Direct Analysis of Extracellular Vesicles in the Conditioned Medium to Study Extracellular Vesicles Secretion with Minimum Sample Processing and Particle Loss.

In-Cell Labeling Coupled to Direct Analysis of Extracellular Vesicles in the Conditioned Medium to Study Extracellular Vesicles Secretion with Minimum Sample Processing and Particle Loss.

Journal: Cells

Published: December 22, 2021

Anti-inflammatory role of GM1 and other gangliosides on microglia.

Anti-inflammatory role of GM1 and other gangliosides on microglia.

Journal: Journal of neuroinflammation

Published: August 19, 2021

Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells.

Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells.

Journal: Stem cell reports

Published: December 02, 2020

Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications.

Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications.

Journal: Frontiers in neuroscience

Published: June 15, 2020

Showing 1-12 of 28

Last Updated: 09/26/2026