Sinead A. O'rourke

Dublin, L, Ireland

Last Updated: 09/26/2026

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Found 22 publications

The Stiffness of Bone Extracellular Matrix Derived Scaffolds Regulates Macrophage Function and Osteogenesis of Mesenchymal Stromal Cells.

The Stiffness of Bone Extracellular Matrix Derived Scaffolds Regulates Macrophage Function and Osteogenesis of Mesenchymal Stromal Cells.

Journal: ACS biomaterials science & engineering

Published: March 07, 2026

IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.

IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.

Journal: JCI insight

Published: February 10, 2026

IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.

IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.

Journal: JCI insight

Published: May 30, 2025

BNT162b2 mRNA vaccination attenuates innate immune function in humans.

BNT162b2 mRNA vaccination attenuates innate immune function in humans.

Journal: Clinical immunology (Orlando, Fla.)

Published: February 10, 2025

Mechano-immunomodulation of macrophages influences the regenerative environment of fracture healing through the regulation of angiogenesis and osteogenesis.

Mechano-immunomodulation of macrophages influences the regenerative environment of fracture healing through the regulation of angiogenesis and osteogenesis.

Journal: Acta biomaterialia

Published: January 22, 2025

Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity.

Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity.

Journal: eLife

Published: December 02, 2024

Human macrophage polarisation and regulation of angiogenesis and osteogenesis is dependent on culture extracellular matrix and dimensionality.

Human macrophage polarisation and regulation of angiogenesis and osteogenesis is dependent on culture extracellular matrix and dimensionality.

Journal: Biochemical and biophysical research communications

Published: October 04, 2024

The Nrf2-HO-1 system and inflammaging.

The Nrf2-HO-1 system and inflammaging.

Journal: Frontiers in immunology

Published: June 29, 2024

Type 1 interferons promote Staphylococcus aureus nasal colonization by inducing phagocyte apoptosis.

Type 1 interferons promote Staphylococcus aureus nasal colonization by inducing phagocyte apoptosis.

Journal: Cell death discovery

Published: April 08, 2024

Staphylococcus aureus suppresses the pentose phosphate pathway in human neutrophils via the adenosine receptor A2aR to enhance intracellular survival.

Staphylococcus aureus suppresses the pentose phosphate pathway in human neutrophils via the adenosine receptor A2aR to enhance intracellular survival.

Journal: mBio

Published: December 18, 2023

Endogenous drivers of altered immune cell metabolism.

Endogenous drivers of altered immune cell metabolism.

Journal: Experimental biology and medicine (Maywood, N.J.)

Published: December 13, 2022

Macrophage metabolic profile is altered by hydroxyapatite particle size.

Macrophage metabolic profile is altered by hydroxyapatite particle size.

Journal: Acta biomaterialia

Published: September 30, 2022

Showing 1-12 of 22

Last Updated: 09/26/2026