Siska Van Belle

Leuven, VLG, Belgium

Last Updated: 09/26/2026

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Found 17 publications

Absence of Ledgf in mouse brain affects the Kmt2a/b and polycomb balance, synaptic transmission and motor function.

Absence of Ledgf in mouse brain affects the Kmt2a/b and polycomb balance, synaptic transmission and motor function.

Journal: Acta neuropathologica communications

Published: August 29, 2025

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.

Journal: Science advances

Published: November 01, 2024

Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.

Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.

Journal: Biochimica et biophysica acta. Reviews on cancer

Published: October 01, 2024

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Journal: European journal of medicinal chemistry

Published: July 29, 2024

LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.

LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.

Journal: Structure (London, England : 1993)

Published: June 02, 2024

BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.

BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.

Journal: Nature communications

Published: April 08, 2024

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.

Journal: Cells

Published: November 24, 2023

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis.

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis.

Journal: Microbiology spectrum

Published: July 19, 2022

Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment.

Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment.

Journal: Bioorganic & medicinal chemistry letters

Published: February 06, 2022

Expansion microscopy allows high resolution single cell analysis of epigenetic readers.

Expansion microscopy allows high resolution single cell analysis of epigenetic readers.

Journal: Nucleic acids research

Published: September 13, 2021

LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection.

LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection.

Journal: Advances in experimental medicine and biology

Published: July 14, 2021

Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.

Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.

Journal: Cells

Published: November 24, 2020

Showing 1-12 of 17

Last Updated: 09/26/2026