Sivakumar Viswanathan
Singapore, Singapore
Last Updated: 09/26/2026
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Found 25 publications
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Journal: Nature
Published: April 18, 2023
Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration.
Journal: Nature communications
Published: December 13, 2022
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues.
Journal: International journal of molecular sciences
Published: July 08, 2022
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
Journal: iScience
Published: February 28, 2022
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Journal: International journal of molecular sciences
Published: February 21, 2022
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome.
Journal: Circulation research
Published: February 09, 2022
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Journal: Nature communications
Published: November 02, 2021
Critical Conditions for Studying Interleukin-11 Signaling In Vitro and Avoiding Experimental Artefacts.
Journal: Current protocols
Published: September 27, 2021
Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts.
Journal: Frontiers in molecular biosciences
Published: July 13, 2021
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.
Journal: Journal of the American Society of Nephrology : JASN
Published: April 29, 2021
The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling.
Journal: eLife
Published: March 27, 2021
Last Updated: 09/26/2026