Sofia Bengtzen

Huddinge, AB, Sweden

Last Updated: 09/26/2026

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Found 14 publications

Targeting IMPDH to inhibit SAMHD1 in KMT2A-rearranged leukaemia.

Targeting IMPDH to inhibit SAMHD1 in KMT2A-rearranged leukaemia.

Journal: Cell cycle (Georgetown, Tex.)
Published: December 16, 2025

Midostaurin response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics.

Midostaurin response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics.

Journal: NPJ precision oncology
Published: September 08, 2025

Addition of hydroxyurea (hydroxycarbamide) enhances the efficacy of fludarabine/cytarabine-based salvage regimens against acute myeloid leukaemia.

Addition of hydroxyurea (hydroxycarbamide) enhances the efficacy of fludarabine/cytarabine-based salvage regimens against acute myeloid leukaemia.

Journal: British journal of haematology
Published: August 10, 2025

Disease-specific epigenetic deregulation of enhancers, transposons, and polycomb targets in acute promyelocytic leukemia.

Disease-specific epigenetic deregulation of enhancers, transposons, and polycomb targets in acute promyelocytic leukemia.

Journal: Genome medicine
Published: May 05, 2025

MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response.

MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response.

Journal: Cancer gene therapy
Published: March 28, 2025

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia.

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia.

Journal: Nature
Published: February 28, 2025

Delineating functional and molecular impact of ex vivo sample handling in precision medicine.

Delineating functional and molecular impact of ex vivo sample handling in precision medicine.

Journal: NPJ precision oncology
Published: June 16, 2023

Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.

Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.

Journal: Journal of internal medicine
Published: August 08, 2022

Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML.

Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML.

Journal: Blood advances
Published: June 01, 2020

AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding.

AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding.

Journal: Blood
Published: July 08, 2019

Bone marrow stroma cells derived from mononuclear cells at diagnosis as a source of germline control DNA for determination of somatic mutations in acute myeloid leukemia.

Bone marrow stroma cells derived from mononuclear cells at diagnosis as a source of germline control DNA for determination of somatic mutations in acute myeloid leukemia.

Journal: Blood cancer journal
Published: October 07, 2017

Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.

Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.

Journal: Epigenetics
Published: May 29, 2014
Showing 1-12 of 14

Last Updated: 09/26/2026